Results 171 to 180 of about 54,231 (299)

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source

Gut microbiota-derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation. [PDF]

Imeta
Wang C, Liu Z, Zhou T, Wu J, Feng F, Wang S, Chi Q, Sha Y, Zha S, Shu S, Qu L, Du Q, Yu H, Yang L, Malashicheva A, Dong N, Xie F, Wang G, Xu K.   +18 more
europepmc   +1 more source

High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells [PDF]

, 2015
Marni E. Cueno, Noriaki Kamio, Keisuke Seki, Tomoko Kurita‐Ochiai, Kuniyasu Ochiai   +4 more
openalex   +1 more source

Antimicrobial‐Releasing Implant Substrates for Combating Oral Biofilms: An In Vitro Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Background and Objectives Peri‐implantitis, a biofilm‐associated inflammatory disease, significantly threatens dental implant longevity. Current treatments face limitations due to biofilm robustness. This study evaluates the efficacy of antimicrobial‐releasing titanium‐silica (Ti/SiO2) composite implant systems against multispecies oral ...
Nur Hidayatul Nazirah Kamarudin, Lars Vanmunster, Brecht Van Hooreweder, Kenneth Siemons, Kristel Bernaerts, Wim Teughels, Annabel Braem, Naiera Zayed   +7 more
wiley   +1 more source

Human Gingival Fibroblasts Rescue Butyric Acid-Induced T-Cell Apoptosis

, 2002
Tomoko Kurita‐Ochiai, Kuniyasu Ochiai, Naoto Suzuki, Kichibee Otsuka, Kazuo Fukushima   +4 more
openalex   +2 more sources

Fermentation of groundnut brittle by Lactococcus lactis produces γ-amino butyric acid and enhances nutritional quality and safety [PDF]

, 2018
Vibhuti Batra, Hitashi Lomash, Abhijit Ganguli   +2 more
openalex   +1 more source

Butyric Acid Fermentation. (II)

Journal of the agricultural chemical society of Japan, 1942
Toshinobu ASAI, Eitaro KOMATSU
openaire   +2 more sources

Peri‐Implant Crevicular Fluid Analysis by Mid‐Infrared Spectroscopy in Peri‐Implantitis—A Pilot Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study aimed to assess biochemical differences in peri‐implant crevicular fluid (PICF) using ATR‐FTIR spectroscopy and multivariate analysis, through a between‐participant comparison of healthy and peri‐implantitis (PI) sites, and a within‐participant comparison of PI‐PICF and GCF from contralateral periodontal healthy teeth ...
Francisco Maligno, Ricardo N. M. J. Páscoa, Pedro S. Gomes   +2 more
wiley   +1 more source

Gut microbiota metabolite butyric acid alleviated <i>Klebsiella Pneumoniae</i> induced lung injury by regulating CX3CR1⁺NK via PI3K/AKT pathway. [PDF]

Burns Trauma
Mu S, Chang M, Shen Y, Wu X, Han Y, Xiang H, Luo Y, Chen Y, Zheng H, Song Z, Tong C.   +10 more
europepmc   +1 more source

In vitro culture, cryopreservation, and field reintroduction of the endangered Mingan thistle

Conservation Biology, EarlyView.
Abstract Current plant conservation efforts are hindered by, for example, poor seed germination, low viability, and insufficient propagation and preservation technologies. To address these problems, we devised an approach to plant conservation that integrates conservation, preservation, and restoration (CPR), which uses advanced in vitro techniques. We
Mukund R. Shukla, Wenlu Bi, Marie‐Claude Roy, Dénommée Nancy, Praveen K. Saxena   +4 more
wiley   +1 more source