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Acetylcholinesterase and Butyrylcholinesterase of Cat
1998Domestic cat (Felis domesticus) pituitary cDNA and leukocyte genomic DNA were amplified by PCR and sequenced for the protein coding regions of butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). ~2 kb of BCHE cDNA and ~4 kb of the ACHE gene with introns were sequenced. Bengal tiger (Panthera tigris) pituitary cDNA was sequenced for BCHE.
Cynthia F. Bartels +3 more
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Production of the Butyrylcholinesterase Knockout Mouse
Journal of Molecular Neuroscience, 2006The butyrylcholinesterase (BChE [EC 3.1.1.8]) knockout mouse is a model for BChE deficiency in humans. The existence of genetic variants of human BChE was discovered after a new muscle relaxant, succinylcholine, was introduced into the practice of medicine in the late 1950s.
Ellen G. Duysen +3 more
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Ionisation of horse serum butyrylcholinesterase
Biochimica et Biophysica Acta (BBA) - Enzymology, 1970Abstract The effect of pH on horse serum cholinesterase (acylcholine acyl-hydrolase, EC 3.1.1.8) catalyzed o- nitrophenyl butyrate hydrolysis shows a non-competitive type of inhibition. The K m value is independent of the pH of the medium, and may be regarded as the true dissociation constant of the ES complex. Its value varies only
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ChemInform Abstract: Resveratrol Derived Butyrylcholinesterase Inhibitors.
ChemInform, 2013AbstractSome of the newly synthesized stilbenes of type (III) are good inhibitors for enzymes acetyl‐ and butyrylcholine esterase (ACE and BCE) for instance, (IIIb) is a good inhibitor for ACE whereas, (IIId) is a 94‐fold stronger inhibitor for BCE than for ACE.
Ralph Kluge +3 more
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Effects of hypophysectomy on acetylcholinesterase and butyrylcholinesterase in the rat
Biochemical Pharmacology, 1983Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities were examined in several tissues of normal and hypophysectomized male and female rats. Significant sex differences in the mean AChE activities of normal rats were observed in the superior cervical ganglion (three times more activity in males) and in serum (50% more activity in ...
Stephen Brimijoin, Joy A. Edwards
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Butyrylcholinesterase in Alzheimer’s Disease
1994Butyrylcholinesterase (BChE, EC.3.1.1.8) is a hydrolytic enzyme of unknown function. Although it is usually considered in conjunction with acetylcholinesterase (AChE), BChE is the product of a different gene, has a much more restricted distribution in the mammalian brain and has no major role in conventional cholinergic neurotransmission.
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Some radiometric microassays for butyrylcholinesterase
Analytical Biochemistry, 1978Abstract A simple method for purifying [ 14 C]butyrylcholine and incubation conditions suitable for estimating butyrylcholinesterase activity are described. Solvent extraction and anion- and cation-exchange procedures for separating butyrylcholine from butyric acid are described and compared.
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Butyrylcholinesterase Transcription Start Site and Promoter
1995Butyrylcholinesterase (BCHE) and acetylcholinesterase (ACHE) genes are expressed independently in adult tissues. This can be inferred from the fact that human BCHE mRNA levels are high in liver, lung, and brain while human ACHE mRNA levels are high in brain and muscle (Jbilo et al, 1994). Other evidence is that AChE and BChE activities do not correlate
Oksana Lockridge +7 more
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Cloning and characterization of the porcine butyrylcholinesterase gene.
1996Section D: Molecular genetics.
Peelman, L.J. +7 more
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