Results 111 to 120 of about 60,574,786 (305)
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
The Effect of Vertical Structure on Exchange Rate Pass-through [PDF]
We introduce an explicit incorporation of local distributors in an analysis of pricing behavior of exporting firms in the pricing-to-market literature. We examine pricing behaviors of exporting firms under four different cases of vertical structure; in ...
Yushi Yoshida
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Exploring the multifaceted functions of APPL in metabolism and memory using Drosophila melanogaster
Molecules and Cells: Amyloid precursor protein (APP) is a single-pass transmembrane protein abundantly expressed in the central nervous system and implicated in familial Alzheimer’s disease, a progressive neurodegenerative disorder that impairs memory.
Dharmendra Kumar Nath, Youngseok Lee
doaj +1 more source
Inline Protein Concentration by Vibratory Single Pass Tangential Flow Filtration
Biotechnology JournalABSTRACTSingle Pass Tangential Flow Filtration (SPTFF) is increasingly used for inline concentration and final formulation in intensified/continuous processes for monoclonal antibody products. However, these modules typically operate at low feed flux, requiring significant membrane area and often complex internal staging to achieve the desired ...
Km Prottoy Shariar Piash +3 more
openaire +2 more sources
Pass-Through of External Factors into Price Indicators In Turkey [PDF]
This study analyzes the pass-through of exchange rate and US Dollar denominated import prices into consumer and producer prices in Turkey. To this end, pricing along a distribution chain framework is utilized and it is estimated by Vector Auto Regression
Caglar Yunculer
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Exchange Rate Pass-Through:Evidence Based on Vector Autoregression with Sign Restrictions [PDF]
: This paper provides cross-country and time-series evidence on the extent of exchange rate pass-through at different stages of distribution - import prices, producer prices and consumer prices - for eight major industrial countries: United States, Japan,
An, Lian
core
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
City of Grants Pass, Oregon water treatment plant facility plan : Final report [PDF]
, 2004 378 pp. Bookmarks supplied by UO. Includes figures. Published May, 2004. Captured March 26, 2008.The purpose of the Grants Pass Water Treatment Plant Facility Plan (WTPFP) is threefold: 1) Define the ability of the existing plant to reliably continue ...
Grants Pass (Or.) +1 more
core +1 more source