Results 71 to 80 of about 60,574,786 (305)

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Grants Pass Notice of Adopted Amendment (2008-05-19)

open access: yes, 2008
22 pp. Adopted 2008-05-19. Department of Land Conservation and Development Notice of Adopted AmendmentAmend the Grants Pass Comprehensive Plan Map for two parcels from Medium Density Residential (MDR) to High-Rise Density Residential (HDR) and the zone ...
Grants Pass (Or.)
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A modified PATH algorithm rapidly generates transition states comparable to those found by other well established algorithms

open access: yesStructural Dynamics, 2016
PATH rapidly computes a path and a transition state between crystal structures by minimizing the Onsager-Machlup action. It requires input parameters whose range of values can generate different transition-state structures that cannot be uniquely ...
Srinivas Niranj Chandrasekaran   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Endogenous Exchange Rate Pass-through when Nominal Prices are Set in Advance [PDF]

open access: yes
This paper develops a model of endogenous exchange rate pass through within an open economy macroeconomic framework, where both pass-through and the exchange rate are simultaneously determined, and interact with one another.
Michael B. Devereux   +2 more
core   +2 more sources

Exchange rate pass-through in Switzerland: Evidence from vector autoregressions [PDF]

open access: yes
This study investigates the pass-through of exchange rate and import price shocks to different aggregated prices in Switzerland. The baseline analysis is carried out with recursively identified vector autoregressive (VAR) models.
Jonas Stulz
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Nuclear translocation of the 4-pass transmembrane protein Tspan8 [PDF]

open access: yesCell Research, 2021
Yuwei Huang   +9 more
openaire   +2 more sources

Exchange Rate Pass-Through to Domestic Prices in Pakistan [PDF]

open access: yes
This paper assesses the extent to which the movements in exchange rate affect domestic wholesale and consumer prices in Pakistan by analyzing data from January 1988 to September 2003.
Zulfiqar Hyder, Sardar Shah
core  

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