Results 111 to 120 of about 43,470,037 (294)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Consumer product safety alert.
Shipping list no.: 98-0090-P.Caption title.Mode of access ...
U.S. Consumer Product Safety Commission.
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Product Variety and Economic Growth: Empirical Evidence for the OECD Countries [PDF]
Utilizing panel data for 19 member countries of the Organization for Cooperation and Development (OECD), we find support for the hypothesis that a greater degree of product variety relative to the United States helps to explain relative per capita GDP ...
Ralf Ruhwedel, By Michael Funke
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A 6-week feeding trial evaluated composite protein mixtures as partial replacements for fish meal (FM) in diets for juvenile yellowtail (Seriola quinqueradiata).
Amal Biswas +4 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Improving product classification through product family segregation [PDF]
Information sources are invaluable when taking decisions in Product design especially at the front end of the design process. Product families if properly classified, the connectivity of product form and interaction of the features assist the designer in
Mohd. Ismail, Mohd. Shuisma +2 more
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