Results 111 to 120 of about 3,303,442 (283)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dietary compounded traditional Chinese medicine residue meal improves laying performance, egg quality, and gut barrier integrity in late-phase laying hens

Poultry Science
This study aimed to investigate the impact of compounded traditional Chinese medicine residue meal (CCMR) on late-phase laying hens, focusing on laying performance, egg quality, albumen gel properties, antioxidant status, immunity, and intestinal barrier
Yujiao Lai, Lina Liu, Zhihao Li, Linlin Li, Rong Wang, Fanbing Zhou, Zhouqingyang Qu, Jing Hu, Shuangshuang Guo, Bingkun Zhang   +9 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Production and Characterization of Novel Photocatalytic Materials Derived from the Sustainable Management of Agro-Food By-Products

Molecules
Porous photocatalysts from agricultural waste, i.e., apricot and peach shell, with titanium dioxide were prepared by a carbonaceous method, the adsorption and photocatalytic degradation and its kinetics about methylene blue (MB) were studied ...
Christina Megetho Gkaliouri, Eleftheria Tsampika Laoudikou, Zacharias Ioannou, Sofia Papadopoulou, Vasiliki Anastasia Giota, Dimitris Sarris   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Adaptability of 2 cellulase producing strains Bacillus sp. SH and Aspergillus oryzae Y21 in whole wheat dough and impact on the quality of whole wheat bread

Food Science and Human Wellness
Compared to refined wheat flour, whole wheat flour contains higher nutrients, but its high content of dietary fiber can have a significant impact on the quality of the final product. Therefore, how to enable consumers to obtain health benefits from whole
Yingli Liu, Shengjie Zhong, Xiaoming Wei, Maosi Fan, Min Cai, Zhengkai Wang, Jing Wang   +6 more
doaj   +1 more source

Synergism of He-3 acquisition with lunar base evolution [PDF]

It is shown how acquisition of He-3 affects Lunar Base development and operation. A four phase evolutionary Lunar Base scenario is summarized with initial equipment mass and resupply requirements. Requirements for various He-3 mining operations are shown
Crabb, Thomas M., Jacobs, Mark K.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Peptides from General By-Products: Unveiling Their Potential Biological Activities in Human Health

Molecules
Peptides are short amino acid chains that can be released from proteins through hydrolysis or fermentation, exhibiting various biological activities, including antioxidant, antihypertensive, anti-inflammatory, and anticancer effects.
Alejandra Colón-Sandoval, Laura A. Contreras-Angulo, Luis A. Cabanillas-Bojórquez, Erick Paul Gutiérrez-Grijalva, Josefina León-Félix, Nayely Leyva-López, Leticia Xochitl López-Martínez, Miriam D. García-Cebreros, José Basilio Heredia   +8 more
doaj   +1 more source