Results 131 to 140 of about 20,748,117 (350)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Impact of overweight on the risk of developing common chronic diseases during a 10-year period.
Archives of Internal Medicine, 2001 BACKGROUND Overweight adults are at an increased risk of developing numerous chronic diseases. METHODS Ten-year follow-up (1986-1996) of middle-aged women in the Nurses' Health Study and men in the Health Professionals Follow-up Study to assess the ...
A. Field +7 more
semanticscholar +1 more source
X-Ray Eclipse Timing in the LMXB EXO0748-676
, 2004 Orbital period changes are an important diagnostic for understanding low mass X-ray binary (LMXB) accretion-induced angular momentum exchange and overall system evolution. We present our most recent results for the eclipse timing of the LMXB EXO0748-676.
Ray, Paul S. +2 more
core +2 more sources
La virtù della scelta ordinata in Agostino d’Ippona
Doctor VirtualisL’ordinamento cosmico rappresenta il punto di riferimento costante dell’agire morale della creatura, che deve misurare le sue scelte preferendo sempre gli esseri-beni oggettivamente superiori a quelli inferiori.
Luigi Oddi
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Dynamo Induced by Time-periodic Force [PDF]
The Astrophysical Journal Letters, 2018 Abstract To understand the dynamo driven by time-dependent flow, e.g., turbulence, we investigate numerically the dynamo induced by time-periodic force in rotating magnetohydrodynamic flow and focus on the effect of force frequency on the dynamo action. It is found that the dynamo action depends on the force frequency.
openaire +2 more sources
The Orbital Period of V368 Aquilae (Nova Aquilae 1936 No. 2)
, 2009 We report observations of the eclipsing classical nova V368 Aql (Nova Aql 1936 No. 2). These data reveal that the orbital period previously published by Diaz & Bruch is an alias of the true orbital period.
Marin, E., Shafter, A. W.
core +1 more source
Medioevo, teorie storiografiche e oggetti intenzionali
Doctor Virtualis, 2010 Il medioevo cinematografico come oggetto essenzialmente teorico, ma dotato di una propria specifica forma di realtà, che ne fa qualcosa definibile, con terminologia fortemente medievale, come oggetto intenzionale.
Riccardo Fedriga
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source