Results 141 to 150 of about 7,595,633 (393)

The Cancer Genome Atlas Pan-Cancer analysis project

Nature Genetics, 2013
Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities among a dozen different types of cancer ...
J. Weinstein, E. Collisson, G. Mills, K. Shaw, B. Ozenberger, K. Ellrott, I. Shmulevich, C. Sander, Joshua M. Stuart   +8 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

OBESIDAD Y CANCER DE MAMA [PDF]

, 2010
Objetivo. Realizamos un estudio de casos y controles para analizar la asociación entre obesidad y riesgo de desarrollar cáncer de mama en mujeres mexicanas. Material y métodos.
Arceo Guzmán, Mario Enrique, De La Cruz Vargas, Jhony Alberto, Héctor Lorenzo, Ocaña Servín   +2 more
core  

A case report: Giant early gastric cancer [PDF]

, 2017
Indexación: Scopus; Scielo.Introducción: El cáncer gástrico es la primera causa de muerte por cáncer, en hombres, en Chile, siendo el adenocarcinoma la variante más frecuente.
Carrasco A., G., Pérez C., A., Vidal A., N.   +2 more
core   +1 more source

The hallmarks of cancer

RNA Biology, 2012
With the advent of next generation sequencing methods and progress in transcriptome analysis, it became obvious that the human genome contains much more than just protein-coding genes.
Tony Gutschner, S. Diederichs
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Diseño y métodos de un estudio de la historia natural de la neoplasia de cuello uterino en la población de una provincia rural de Costa Rica: el Proyecto de Guanacaste

Revista Panamericana de Salud Pública
En este documento se informa sobre la fase de inscripción de un estudio de la historia natural de la neoplasia de cuello uterino basado en la población de Guanacaste, una provincia rural de Costa Rica con tasas constantemente elevadas de cáncer ...
Rolando Herrero, Mark H. Schiffman, Concepción Bratti, Allan Hildesheim, Ileana Balmaceda, Mark E. Sherman, Mitchell Greenberg, Fernando Cárdenas, Víctor Gómez, Kay Helgesen, Jorge Morales, Martha Hutchinson, Laurie Mango, Mario Alfaro, Nancy W. Potischman, Sholom Wacholder, Christine Swanson, Louise A. Brinton   +17 more
doaj   +1 more source

CD44-high neural crest stem-like cells are associated with tumour aggressiveness and poor survival in neuroblastoma tumours [PDF]

, 2019
BACKGROUND: Neuroblastoma is a paediatric tumour originated from sympathoadrenal precursors and characterized by its heterogeneity and poor outcome in advanced stages.
Aguilar Morante, Diana, Cabello Laureano, Rosa, Colmenero Repiso, Ana, Gómez Muñoz, María A., Márquez Vega, Catalina, Pardal Redondo, Ricardo, Ramírez Villar, Gema, Rodríguez Prieto, Ismael, Vega Moreno, Francisco Manuel   +8 more
core   +1 more source

Cancer treatment and survivorship statistics, 2019

Ca, 2019
The number of cancer survivors continues to increase in the United States because of the growth and aging of the population as well as advances in early detection and treatment.
K. D. Miller, Leticia M. Nogueira, A. Mariotto, J. Rowland, K. R. Yabroff, C. Alfano, A. Jemal, J. Kramer, R. Siegel   +8 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source