Results 161 to 170 of about 3,901,272 (281)
Scientific ReportsAt the molecular level, triple-negative breast cancer (TNBC) is frequently categorized as PAM50 basal-like subtype, but despite the advances in molecular analyses, the clinical outcome for these subtypes is uncertain.
Mireya Cisneros-Villanueva +9 more
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MedwaveIntroduction Breast cancer survivors often experience pre and post-treatment physical and psychological symptoms, negatively affecting their quality of life.
Francia Martínez +8 more
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Atención del cáncer a refugiados y población desplazada: una crisis humanitaria que se avecina
Gaceta Mexicana de OncologíaPlease the the content in english.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2021 La carga del cáncer de mama en América Latina ha aumentado en las últimas décadas. Se ha incrementado la incidencia y mortalidad del cáncer de mama en Quito.
Troya Proaño, Ana Cristina
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
El futuro de la financiación de la investigación del cáncer en países de bajos y medianos ingresos
Gaceta Mexicana de Oncolog�aLos recientes acontecimientos en todo el mundo, y en particular en EE.UU., han generado una enorme preocupación sobre el futuro de la salud global y planetaria. La retirada de EE.UU. de la Organización Mundial de la Salud (OMS), junto con la suspensión de numerosos paneles de revisión de los Institutos Nacionales de Salud (NIH) y la retirada de la ...
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
El cáncer constituye una enfermedad que afecta a todo tipo de especies multicelulares desde los animales más pequeños y grandes hasta el ser humano (Kapsetaki et al., 2023).
Pepinós Valle, Jocelyne Cristina
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