Results 161 to 170 of about 3,946,056 (287)

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

El Cáncer en Trujillo 1984-1987: Estudio de Incidencia y Mortalidad

open access: yes, 1992
Este estudio presenta los resultados de incidencia y mortalidad del Registro de Cáncer de Base Poblacional de la ciudad de Trujillo para el período 1984-1987, reconociendo a las neoplasias malignas como un problema creciente de salud pública en el Perú ...
Albújar Baca, Pedro Félix
core  

LncRNA SOX9-AS1 triggers a transcriptional program involved in lipid metabolic reprogramming, cell migration and invasion in triple-negative breast cancer

open access: yesScientific Reports
At the molecular level, triple-negative breast cancer (TNBC) is frequently categorized as PAM50 basal-like subtype, but despite the advances in molecular analyses, the clinical outcome for these subtypes is uncertain.
Mireya Cisneros-Villanueva   +9 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Cáncer de ovario

open access: yes, 2022
El cáncer de ovario tiene la malignidad ginecológica más letal que los demás cáncer, es asintomático en estadios tempranos y no tiene estrategias de tamización.
Mamani Centeno, Edson
core  

Physical exercise in Chilean breast cancer survivors: Qualitative study of barriers, facilitators and preferences

open access: yesMedwave
Introduction Breast cancer survivors often experience pre and post-treatment physical and psychological symptoms, negatively affecting their quality of life.
Francia Martínez   +8 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

El futuro de la financiación de la investigación del cáncer en países de bajos y medianos ingresos

open access: yesGaceta Mexicana de Oncolog�a
Los recientes acontecimientos en todo el mundo, y en particular en EE.UU., han generado una enorme preocupación sobre el futuro de la salud global y planetaria. La retirada de EE.UU. de la Organización Mundial de la Salud (OMS), junto con la suspensión de numerosos paneles de revisión de los Institutos Nacionales de Salud (NIH) y la retirada de la ...
openaire   +2 more sources

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