Results 171 to 180 of about 3,946,056 (287)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Atención primaria y detección del cáncer colorrectal
Atención Primaria, 2017 Mercè Marzo Castillejo +3 more
openaire +3 more sources
Necesidades en la atención integral del cáncer en México
Gaceta Mexicana de Oncolog�a, 2023 openaire +2 more sources
Gaceta Mexicana de Oncolog�aAntecedentes: Toda persona sin trabajo a causa del cáncer constituye una pérdida económica para la sociedad. Las medidas más notables para cuantificar es el costo de productividad. Objetivo: Conocer los gastos indirectos por el tratamiento de irradiación en cáncer de cuello uterino y si estos están asociados o relacionados con factores clínicos ...
openaire +2 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2009 Presentación que explica en qué consiste el cáncer, abordando más adelante temas como el factor genético relacionado con esta enfermedad y la metástasis, así como los tipos de cáncer que atacan al sistema nervioso.Cancer is a process of uncontrolled ...
Clavijo Montoya, Hernando Augusto
core
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Dataset de afectos positivos y negativos en pacientes con cáncer de mama.
Datos pertenecientes a un estudio instrumental de las Escalas de Afecto Negativo y Positivo (NAPAS) en mujeres con diagnóstico de cáncer de ...
Soria-Reyes, Lorena M. +4 more
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source