Results 71 to 80 of about 5,704,490 (283)

A comprehensive cross-sectional survey to identify barriers and facilitators of cervical cancer screening in women with HIV in Guangxi, China

Infectious Agents and Cancer, 2022
Background Co-infection with HIV is a strong risk factor for cervical cancer development. It is unknown whether women with HIV in Guangxi, China are utilizing currently available cervical cancer screening services, what barriers they face, and if they ...
Ran Zhao, Shujia Liang, Deanna Teoh, Yunqing Fei, Xianwu Pang, Shalini Kulasingam   +5 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Variantes del Papilomavirus Humano 16 y su asociación con el HLA en cáncer cervical [PDF]

, 2010
El cáncer cervical es el segundo cáncer más común en mujeres en el mundo y es el principal cáncer en mujeres en países en desarrollo. La infección persistente por los genotipos oncogénicos del Virus del Papiloma Humano (VPH) es la causa necesaria para el
Sánchez Vásquez, Gloria I, Milena Bedoya, Astrid, Flórez García, Víctor, Montiel, Jehidys   +3 more
core  

Prevalencia de anormalidades en la citología cervical en tres grupos poblacionales de mujeres en Popayán, Colombia 2003 - 2005 Prevalence of cervical cytological abnormalities on three population groups of women in Popayán, Colombia 2003 - 2005

Revista Colombiana de Obstetricia y Ginecología, 2008
El cáncer cervical es una enfermedad prevenible, sin embargo su erradicación todavía está lejana. La citología no siempre detecta la infección por virus de papiloma humano (HPV) y no predice su comportamiento; es necesario delimitar grupos de riesgo y ...
Myriam Bravo de Insuasty, José Vicente Erazo, Ana María Álvarez, María Isabel Casas, Ofelia Ortiz de Collazos, Jaime Álvarez-Soler   +5 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Perspectivas de control de cáncer cervical en el siglo XXI [PDF]

, 2003
La morbilidad y mortalidad de cáncer cervical ha decrecido sustancialmente durante los últimos 50 años, debido principalmente a programas organizados de detección oportuna de cáncer basados en citología, particularmente en países con altos y medianos ...
Ferenczy, Alex, Franco, Eduardo L., Duarte-Franco, Eliane   +2 more
core  

Risk factors for cervical cancer among HPV positive women in Mexico Factores de riesgo de cáncer cervical en mujeres VPH positivas en México

Salud Pública de México, 2008
OBJECTIVE: To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico.
Yvonne N Flores, David M Bishai, Keerti V Shah, Eduardo Lazcano-Ponce, Attila Lörincz, Mauricio Hernández, Daron Ferris, Jorge Salmerón   +7 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Perspectivas de prevención primaria de cáncer cervical en países en desarrollo [PDF]

, 2003
Los tipos de virus de papiloma humano (VPH) que causan cáncer cervical son sexualmente transmisibles, pero existe muy poca evidencia sobre que la infección pueda ser evitada por cambios en las conductas sexuales de alto riesgo, tales como el uso del ...
Franceschi, Silvia, Plummer, Martyn, Clifford, Gary   +2 more
core  

Cervical cancer screening among HIV-positive women in urban Uganda: a cross sectional study

BMC Women's Health, 2022
Background Women living with Human Immunodeficiency Virus (HIV) are at a high risk for early development of cervical cancer. Adherence to cervical cancer prevention strategies in this population is vital for the early detection and treatment of cervical ...
Najjuka Sarah Maria, Connie Olwit, Mark Mohan Kaggwa, Rose Chalo Nabirye, Tom Denis Ngabirano   +4 more
doaj   +1 more source