Results 11 to 20 of about 222,078 (214)
Clinical-epidemiological characterization of colorectal carcinoma
Revista Científica Estudiantil 2 de Diciembre, 2021 Introduction: colon and rectal cancer is among the leading causes of cancer death worldwide in recent years. Objective: to characterize clinically and epidemiologically colorectal cancer.
Norey Barbaro Ochoa Benítez +2 more
doaj
Cáncer de Colon en las fronteras de México
Población y Salud en Mesoamérica, 2020 Introducción: Uno de los retos que se identifican para diseñar estrategias efectivas de control del cáncer de colon a escala global es el contar con instrumentos de monitoreo que permitan medir su evolución.
Jose Luis Manzanares Rivera
doaj +1 more source
To have a colostomy: transformation corporality
Cultura de los Cuidados, 2017 Justification: The person with colon cancer with a colostomy required to recognize your physical body felt transformed and lived corporeality. Objetives: Describe transformative processes and meanings of corporeality, and meaning attributed to a ...
Ghandy Ponce Gómez +2 more
doaj +1 more source
Revista Médica Clínica Las CondesResumen: El cáncer colorrectal es el tercero en frecuencia a nivel mundial. En Chile, durante el año 2020 se diagnosticaron 5 914 nuevos casos. Su presentación obstructiva es una amenaza a la vida por la alteración fisiológica, sumado a su presentación ...
Mario Abedrapo, MD, Víctor Cortés, MD
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source