Results 101 to 110 of about 67,909 (325)
Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration
Advanced Science, EarlyView.Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin +7 more
wiley +1 more source
Health disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian +3 more
wiley +1 more source
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Advanced Science, EarlyView.Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Caso clínico de cáncer de mama localmente avanzado [PDF]
, 2016 Se presenta un caso clínico de cáncer de mama en el que existe invasión de la cadena mamaria interna sin previa afectación axilar. Se trata de una mujer de 49 años que mediante autoexploración se detecta un nódulo en la mama derecha.
Moreno Pulido, Silvia +1 more
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Advanced Science, EarlyView.This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source
pequeñas dosis de roentgenterapia profunda en las metástasis óseas de los cánceres epiteliales
Cirugía del Uruguay, 2020 Presentado en sesión de 5 de julio de ...
Armando Loubejac
doaj
Desarrollo e implementación de guías para el aseguramiento de la calidad en el tamizaje de cáncer de mama: la experiencia europea [PDF]
, 2013 In Europe, as in many other regions of the world, breast cancer is a major cause of suffering and death. Early detection of breast cancer by systematic mammography screening can find lesions for which treatment is more effective and generally more ...
Arrossi, Silvina, von Karsa, Lawrence
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