Results 211 to 220 of about 61,158,239 (269)

HER2‐Targeted AIE Nanotheranostics Overcome SHR‐A1811 Resistance via Immunogenic Pyroptosis and Tumor‐Associated Macrophage Reprogramming in Breast Cancer

Small, EarlyView.
HER2‐targeted AIE780‐A1811 nanoparticles self‐assemble via amide coupling of a mitochondria‐directed photosensitizer with the ADC SHR‐A1811. Upon 660 nm irradiation, they generate ROS, photothermal effects, and controlled drug release, inducing immunogenic pyroptosis and M2‐to‐M1 macrophage reprogramming. This dual action remodels the immunosuppressive
Xiaohong Liu, Nisha Wu, Zaihui Peng, Guozhi Zhang, Lin Ren, Qiuyun Li, Jie Xiao, Jing He, Yuxiuzi Xiao, Li Ma, Yi Zhang, Ying Gong, Xiaowei Qi   +12 more
wiley   +1 more source

Constructing Difference: Maternal Boundary‐Work in Science‐Based and Natural Mom Groups on Facebook

Symbolic Interaction, EarlyView.
Boundary‐work describes the activities of social groups as they seek to differentiate themselves from others to establish credibility, authority, or to protect their interests. While a growing body of literature explores occupational boundary‐work in health care, limited research has focused on how lay actors practice boundary‐work online.
Darryn DiFrancesco
wiley   +1 more source

Temporal trend and spatial analysis of breast cancer mortality in Paraná, 2012-2021. [PDF]

Epidemiol Serv Saude
Santos SGPD, Cruz CFR, Prezotto KH, Moreira RC, Galdino MJQ, Oliveira RR, Scholze AR, Melo EC.   +7 more
europepmc   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

The impact on body image and quality of life in breast cancer patients. [PDF]

Rev Bras Enferm
Mastrangelli AKF, Pinto VL, Elias S.
europepmc   +1 more source

Thrombocytosis and tumour distribution predict outcome in dogs with hepatocellular carcinoma: A multi‐institutional retrospective analysis

Veterinary Record, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik, MacKenzie A. Pellin, Dawn M. Clarke   +2 more
wiley   +1 more source

Zn2+‐Driven Self‐Amplifying Nanoplatform Enables Cascade Photothermal–Gene Therapy via Mitochondrial Disruption

VIEW, EarlyView.
A Zn2+‐activated nanoplatform enables self‐amplifying photothermal–gene therapy by disrupting mitochondria and releasing siRNA, creating a feedback loop that sensitizes tumor cells and enhances ablation in vitro and in vivo. This metal ion‐driven strategy offers a new approach for cascade‐amplified nanotherapeutics. ABSTRACT The therapeutic efficacy of
Zhi Li, Yuhong Chen, Youfei Zhang, Luzhen Huai, Xingzhou Zhu, Xue Mo, Jiahao Wang, Kui Zeng, Jie Wang   +8 more
wiley   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Breast cancer in northern Peru: molecular subtypes and HER2 low. [PDF]

Rev Peru Med Exp Salud Publica
Gómez-Rázuri K, Abad-Licham M, Astigueta J, Moreno J.   +3 more
europepmc   +1 more source

Depth and Procedure Specific Effects of Antimicrobial Versus Conventional Sutures on Surgical Site Infection: A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
Antimicrobial sutures may be particularly beneficial in colorectal and abdominal procedures, where reductions in deep SSI may offset the additional suture cost. Several studies also reported favorable wound‐healing outcomes. ABSTRACT Background Surgical site infections (SSIs) are common postoperative complications that delay wound healing and increase ...
Ryan Muakkassa, Andrew Roach, Ahmed Adham R. Elsayed, Marc D. Basson   +3 more
wiley   +1 more source