Results 1 to 10 of about 5,139,728 (295)
PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer.
New England Journal of Medicine, 2022 BACKGROUND Neoadjuvant chemotherapy and radiation followed by surgical resection of the rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is caused by a deficiency in mismatch repair.
A. Cercek +31 more
semanticscholar +1 more source
Journal of Clinical Oncology, 2022 PURPOSE To ascertain if preoperative short-term radiotherapy followed by chemotherapy is not inferior to a standard schedule of long-term chemoradiotherapy in patients with locally advanced rectal cancer.
Jing Jin +34 more
semanticscholar +1 more source
Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
The Journal of the National Comprehensive Cancer Network, 2022 This selection from the NCCN Guidelines for Rectal Cancer focuses on management of malignant polyps and resectable nonmetastatic rectal cancer because important updates have been made to these guidelines.
A. Benson +39 more
semanticscholar +1 more source
Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer.
Cancer Cell, 2022 Standard cancer therapy targets tumor cells without considering possible damage on the tumor microenvironment that could impair therapy response. In rectal cancer patients we find that inflammatory cancer-associated fibroblasts (iCAFs) are associated ...
Adele M. Nicolas +25 more
semanticscholar +1 more source
EPIDEMIOLOGICAL PARALLELS OF RECTAL CANCER INCIDENCE IN KAZAKHSTAN AND KYRGYZSTAN
Актуальные проблемы теоретической и клинической медицины, 2022 Background and Objectives: Of the colorectal malignant tumors, 30 percent will arise in the rectum. The incidence of rectal cancer is increasing with the change of diet habit and genetic factors. The etiology of colon and rectal cancer is a bit different.
E. Makimbetov +9 more
doaj +1 more source
The importance of MRI for rectal cancer evaluation.
Surgical oncology, 2022 Magnetic resonance imaging (MRI) has gained increasing importance in the management of rectal cancer over the last two decades. The role of MRI in patients with rectal cancer has expanded beyond the tumor-node-metastasis (TNM) system in both staging and ...
Maria Clara Fernandes +2 more
semanticscholar +1 more source
Frontiers in Genetics, 2022 Rectal cancer is a malignant tumor with poor prognosis. Identification of prognostic biomarkers is needed to improve overall survival of rectal cancer patients. Here, we firstly identified miR-20a-5p significantly classifying high-risk group and low-risk
Tingting Tang +6 more
doaj +1 more source
Frontiers in Oncology, 2021 Rectal cancer (RC) is the leading cause of tumor-related death among both men and women. The efficacy of immunotherapy for rectal cancer is closely related to the immune infiltration level.
Changjing Cai +25 more
doaj +1 more source
SNHG17 Serves as an Oncogenic lncRNA by Regulating the miR-361-3p/STC2 Axis in Rectal Cancer
Frontiers in Genetics, 2021 Long noncoding RNA (lncRNA) have been reported to be crucial regulators for carcinogenesis, including rectal cancer. This work aimed to explore the roles and associated mechanisms of small nucleolar RNA host gene 17 (SNHG17) in rectal cancer.
Fuda Huang +8 more
doaj +1 more source
Frontiers in Oncology, 2023 With the advancement of imaging and pathological diagnostic methods, it is not uncommon to see synchronous gastrointestinal stromal tumors (GIST) and other primary cancers, the most common of which are synchronous gastric cancer and gastric GIST. However,
Jun Ma +5 more
doaj +1 more source