Results 161 to 170 of about 6,225,903 (287)

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Cell Reports, 2018
C. Ricketts, Aguirre A. de Cubas, Huihui Fan, Christof C. Smith, M. Lang, Ed Reznik, R. Bowlby, E. Gibb, Rehan Akbani, R. Beroukhim, D. Bottaro, T. Choueiri, R. Gibbs, A. Godwin, S. Haake, A. Hakimi, E. Henske, J. Hsieh, T. Ho, R. Kanchi, B. Krishnan, David J. Kwaitkowski, Wembin Lui, M. Merino, G. Mills, J. Myers, M. Nickerson, V. Reuter, L. Schmidt, C. Shelley, Hui Shen, B. Shuch, S. Signoretti, R. Srinivasan, P. Tamboli, G. Thomas, B. Vincent, C. Vocke, D. Wheeler, Lixing Yang, William T. Kim, A. G. Robertson, P. Spellman, W. Rathmell, W. Linehan   +44 more
semanticscholar   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.

New England Journal of Medicine, 2003
J. Yang, Leah R. Haworth, R. Sherry, P. Hwu, D. Schwartzentruber, S. Topalian, S. Steinberg, Helen X. Chen, S. Rosenberg   +8 more
semanticscholar   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

Marine-Derived Compounds: A New Horizon in Cancer, Renal, and Metabolic Disease Therapeutics. [PDF]

Mar Drugs
Zhang J.
europepmc   +1 more source

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

Cell, 2018
S. Turajlic, Hang Xu, K. Litchfield, A. Rowan, T. Chambers, J. López, D. Nicol, T. O'brien, J. Larkin, S. Horswell, M. Stares, L. Au, M. Jamal-Hanjani, B. Challacombe, A. Chandra, S. Hazell, Claudia Eichler-Jonsson, A. Soultati, S. Chowdhury, S. Rudman, Joanna Lynch, A. Fernando, G. Stamp, E. Nye, Faiz Jabbar, L. Spain, S. Lall, R. Guarch, M. Falzon, I. Proctor, L. Pickering, M. Gore, T. Watkins, S. Ward, A. Stewart, R. DiNatale, Maria F. Becerra, Ed Reznik, J. Hsieh, T. Richmond, G. Mayhew, S. Hill, Catherine D. McNally, Carol Jones, Heidi Rosenbaum, S. Stanislaw, Daniel L Burgess, Nelson R. Alexander, C. Swanton   +48 more
semanticscholar   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source