Results 1 to 10 of about 591,781 (298)

Oncometabolites in renal cancer [PDF]

Nature Reviews Nephrology, 2019
The study of cancer metabolism has evolved vastly beyond the remit of tumour proliferation and survival with the identification of the role of ‘oncometabolites’ in tumorigenesis. Simply defined, oncometabolites are conventional metabolites that when aberrantly accumulated have pro-oncogenic functions.
Grant D Stewart, Christian Frezza, Stewart Grant D   +2 more
exaly   +3 more sources

Renal-Cell Cancer

Ca-A Cancer Journal for Clinicians, 1966
Harry Grabstald
exaly   +3 more sources

Renal cancer

The Lancet, 2016
The diagnosis and management of renal cell carcinoma have changed remarkably rapidly. Although the incidence of renal cell carcinoma has been increasing, survival has improved substantially. As incidental diagnosis of small indolent cancers has become more frequent, active surveillance, robot-assisted nephron-sparing surgical techniques, and minimally ...
Capitanio Umberto, MONTORSI , FRANCESCO
  +9 more sources

Safety, activity, and pharmacokinetics of camrelizumab in advanced Asian melanoma patients: a phase I study

BMC Cancer, 2022
Background Anti-programmed cell death receptor-1 (PD-1) monotherapy is the standard treatment for metastatic melanoma in current. Camrelizumab is a humanized IgG4 anti-PD-1 monoclonal antibody whose safety and efficacy have not been reported in advanced ...
Li Zhou, Xiaowen Wu, Zhihong Chi, Lu Si, Xinan Sheng, Yan Kong, Lili Mao, Bin Lian, Bixia Tang, Xieqiao Yan, Xuan Wang, Xue Bai, Siming Li, Xiaoting Wei, Juan Li, Qing Yang, Jun Guo, Chuanliang Cui   +17 more
doaj   +1 more source

Chemotherapy combined with antiangiogenic drugs as salvage therapy in advanced melanoma patients progressing on PD-1 immunotherapy

Translational Oncology, 2021
Background: This study aimed to evaluate the effect of salvage therapy with nab-paclitaxel (nab-p) or temozolomide (TMZ) combined with antiangiogenic drugs in programmed death 1 (PD-1) inhibitor-resistant patients with unresectable metastatic melanoma ...
Xuan Wang, Weiran Xu, Zhihong Chi, Lu Si, Xinan Sheng, Yan Kong, Li Zhou, Lili Mao, Bin Lian, Bixia Tang, Xieqiao Yan, Xue Bai, Chuanliang Cui, Jun Guo   +13 more
doaj   +1 more source

What do end-users want to know about managing the performance of healthcare delivery systems? Co-designing a context-specific and practice-relevant research agenda

Health Research Policy and Systems, 2021
Background Despite increasing interest in joint research priority-setting, few studies engage end-user groups in setting research priorities at the intersection of the healthcare and management disciplines.
Jenna M. Evans, Julie E. Gilbert, Jasmine Bacola, Victoria Hagens, Vicky Simanovski, Philip Holm, Rebecca Harvey, Peter G. Blake, Garth Matheson   +8 more
doaj   +1 more source

Surgical Outcomes of Vaginal or Cervical Melanoma

Frontiers in Surgery, 2022
Objective: To evaluate the effectiveness of radical resection compared with non-radical resection for vaginal or cervical melanoma.Methods: We retrospectively analysed the clinical data of post-operative patients with primary lower genital tract melanoma
Hui Tian, Xuan Wang, Bin Lian, Lu Si, Min Gao, Hong Zheng, Zhihong Chi, Yan Kong, Lili Mao, Xue Bai, Bixia Tang, Xieqiao Yan, Siming Li, Li Zhou, Jie Dai, Yangchun Sun, Lingying Wu, Jun Guo, Chuanliang Cui   +18 more
doaj   +1 more source

Biomarkers in renal cancer [PDF]

Virchows Archiv, 2014
Treatment options for primary and metastatic renal cancer are increasing. Accurate data from the pathological examination of renal cancer specimens aid clinicians in stratifying patients for surveillance and adjuvant therapies. This review focuses on biomarkers in diagnosis, prognosis and prediction of the biologic behavior of renal tumors which should
Moch, Holger, Srigley, John, Delahunt, Brett, Montironi, Rodolfo, Egevad, Lars, Tan, Puay Hoon   +5 more
openaire   +2 more sources

miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

Journal of Experimental & Clinical Cancer Research, 2019
Background Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in melanoma.
Huan Tang, Meng Ma, Jie Dai, Chuanliang Cui, Lu Si, Xinan Sheng, Zhihong Chi, Longwen Xu, Sifan Yu, Tianxiao Xu, Junya Yan, Huan Yu, Lu Yang, Yan Kong, Jun Guo   +14 more
doaj   +1 more source

Identification of coexistence of BRAF V600E mutation and EZH2 gain specifically in melanoma as a promising target for combination therapy

Journal of Translational Medicine, 2017
Background Coexistence of enhancer of zeste homolog 2 (EZH2) and BRAF gene aberrations has been described in many cancer types. In this study, we aim to explore the coexistence status of BRAF V600E mutation and the copy number variation of EZH2 and ...
Huan Yu, Meng Ma, Junya Yan, Longwen Xu, Jiayi Yu, Jie Dai, Tianxiao Xu, Huan Tang, Xiaowen Wu, Siming Li, Bin Lian, Lili Mao, Zhihong Chi, Chuanliang Cui, Jun Guo, Yan Kong   +15 more
doaj   +1 more source