Results 31 to 40 of about 591,781 (298)

Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer [PDF]

open access: yes, 2012
UCAN Cancer Charity (www.ucanhelp.org.uk) and MacMillan Cancer Charity (www.macmillan.org.uk) helped design and conduct the study.Peer ...
Hilvano-Cabungcal, Ana M.   +27 more
core   +1 more source

Primary malignant melanoma of the esophagus: A retrospective analysis of clinical features, management, and survival of 76 patients

open access: yesThoracic Cancer, 2019
Background Primary malignant melanoma of the esophagus (PMME) is rare. Patients with advanced melanoma of esophageal origin tend to have lower response rates to traditional therapies than those with other melanomas.
Xuan Wang   +10 more
doaj   +1 more source

Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome

open access: yes, 2013
Renal cell carcinoma (RCC) is the most deadly of urological malignancies. Metastatic disease affects one third of patients at diagnosis with a further third developing metastatic disease after extirpative surgery.
Antony C P Riddick   +24 more
core   +1 more source

Preliminary study on the role of the C5orf46 gene in renal cancer

open access: yesTranslational Oncology, 2022
Background: C5orf46 has been found to have antibacterial and anti-inflammatory effects via sequencing and microarray technologies, but its effects on cancer are unclear.
Ming Ma   +6 more
doaj   +1 more source

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma [PDF]

open access: yes, 2010
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over)expression has been linked to several human malignancies. Here, we studied a possible association between EZH2 expression and prognosis in patients with
Johannes Hüsing   +29 more
core   +1 more source

Management of Melanoma Brain Metastases in the Era of Targeted Therapy

open access: yesJournal of Skin Cancer, 2011
Disseminated metastatic disease, including brain metastases, is commonly encountered in malignant melanoma. The classical treatment approach for melanoma brain metastases has been neurosurgical resection followed by whole brain radiotherapy ...
Daniela Gonsalves Shapiro   +1 more
doaj   +1 more source

A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo

open access: yesNature Communications, 2021
The lack of animal models for some human diseases precludes our understanding of disease mechanisms and our ability to test new therapies in vivo. Here the authors present a tissue bioengineering strategy for the study of a rare kidney tumor called ...
J. O. R. Hernandez   +15 more
doaj   +1 more source

Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer

open access: yes, 2008
Background Enhanced activity of histone deacetylases (HDAC) is associated with more aggressive tumour behaviour and tumour progression in various solid tumours.
Dietel Manfred   +21 more
core   +1 more source

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

open access: yesScientific Reports, 2022
Proteolytic activation of the renal epithelial sodium channel (ENaC) is increased by aldosterone. The aldosterone-sensitive protease remains unidentified.
Rikke Zachar   +11 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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