Results 41 to 50 of about 591,781 (298)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Soft drink and juice consumption and renal cell carcinoma incidence and mortality in the European Prospective Investigation into Cancer and Nutrition [PDF]

, 2021
Background: Renal cell carcinoma (RCC) accounts for more than 80% of kidney cancers in adults, and obesity is a known risk factor. Regular consumption of sweetened beverages has been linked to obesity and several chronic diseases, including some types of
Tjonneland, Anne, Petersen, Kristina Elin Nielsen,, Catalano, Alberto, Jayanth, Nick, Lujan-Barroso, Leila,, Bergmann, Manuela M., Schulze, Matthias Bernd (Prof. Dr.), Bergmann, Manuela M,, Huybrechts, Inge,, Rodríguez Barranco, Miguel, Clasen, Joanna L.,, Petersen, Kristina, Huybrechts, Inge, Jenab, Mazda,, Heath, Alicia K,, Heath, Alicia K., Jenab, Mazda, Catalano, A, Santiuste, Carmen, Heath, Alicia K.,, Standahl Olsen, Karina, Santiuste, Carmen,, Ljungberg, Börje,, Lund University., Masala, Giovanna, Krogh, Vittorio, Skeie, Guri, Jayanth, Nick P, Axelson, Håkan, Clasen, Johanna L, Ljungberg, Börje, Masala, Giovanna,, Tjønneland, Anne, Standahl Olsen, Karina,, Weiderpass, Elisabete,, Watts, Eleanor L.,, Katzke, Verena, Watts, Eleanor L, Amiano, Pilar, Schulze, Matthias B.,, Skeie, Guri,, Heath, Alicia, Axelson, Håkon, Rodríguez-Barranco, Miguel, Tjønneland, Anne,, Gurrea, Aurelio Barricarte, Watts, Eleanor L,, Watts, Eleanor, Clasen, Joanna L, Weiderpass, Elisabete, Schulze, Matthias B,, Clasen, Joanna, Pasanisi, Fabrizio, Schulze, Matthias B., Watts, Eleanor L., Ramne, Stina,, Muller, David, Riboli, Elio, Tumino, Rosario, Srour, Bernard,, Bergmann, Manuela M, Brustad, Magritt,, Amiano, Pilar,, Katzke, Verena,, Catalano, Alberto,, Riboli, Elio,, Bergmann, Manuela, Muller, David C., Heath, Alicia K, Overvad, Kim,, Schulze, Matthias B, Pasanisi, Fabrizio,, Schulze, Matthias, Olsen, Karina Standahl, Muller, David C,, Srour, Bernard, Tumino, Rosario,, Petersen, Kristina E N, Petersen, Kristina Elin Nielsen, Jayanth, Nick P,, Barricarte Gurrea, Aurelio, Jayanth, Nick P., Clasen, Joanna L., Axelson, Hakan,, Barricarte Gurrea, Aurelio,, Clasen, Joanna L,, Rodríguez-Barranco, Miguel,, Overvad, Kim, Olsen, Karina Standahl,, Brustad, Magritt, Luján-Barroso, Leila, Muller, David C, Jayanth, Nick P.,, Muller, David C.,, Ramne, Stina, Krogh, Vittorio,, Bergmann, Manuela M.,   +96 more
core   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Pazopanib versus sunitinib in Chinese patients with locally advanced or metastatic renal cell carcinoma: pooled subgroup analysis from the randomized, COMPARZ studies

BMC Cancer, 2020
Background We performed a pooled analysis of the COMPARZ study assessing efficacy and safety of pazopanib versus sunitinib in treatment-naïve Chinese patients with locally advanced and/or metastatic renal cell carcinoma (a/mRCC).
Xinan Sheng, Jie Jin, Zhisong He, Yiran Huang, Aiping Zhou, Jinwan Wang, Xiubao Ren, Dingwei Ye, Xu Zhang, Shukui Qin, Fangjian Zhou, Binhui Wang, Jun Guo   +12 more
doaj   +1 more source

Synchronous primary gastric and renal tumors: a case report

Future Science OA, 2023
Synchronous multiple primary cancers of the stomach and kidney are very rare, only 45 cases of synchronous multiple primary cancers of the stomach and kidney had been reported in the literature up until 2020.
Salma Merhaben, Asma Ben Mohamed, Amal Khsiba, Moufida Mahmoudi, Salwa Nechi, Emna Chelbi, Houda Kilani, Manel Yakoubi, Mohamed Lamine Hamzaoui, Mouna Medhioub, Mohamed Moussadak Azouz   +10 more
doaj   +1 more source

The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma

, 2012
Background: Epithelial-to-mesenchymal transition (EMT) has recently been implicated in the initiation and progression of renal cell carcinoma (RCC). Some mRNA gene expression studies have suggested a link between the EMT phenotype and poorer clinical ...
Antony C P Riddick, Stewart Grant D., Faratian Dana, Theodoulou Marianna, Grant D Stewart, Dana Faratian (171110), O'Mahony Fiach C., O'Mahony, Fiach C, James Varley (181899), David J. Harrison (171106), Jyoti Nanda (181902), Riddick, Antony C P, Varley James, Marianna Theodoulou, Dana Faratian, Varley, James, Riddick Antony C. P., Harrison David J., Fiach C O'Mahony, Antony C. P. Riddick (145315), Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Faratian, Dana, Riddick, Antony C. P., Nanda Jyoti, Marianna Theodoulou (181905), Grant D. Stewart (145312), Theodoulou, Marianna, Nanda, Jyoti, Stewart, Grant D., James Varley, Stewart, Grant D, Fiach C. O'Mahony (181892), Harrison, David J.   +35 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Re-Evaluating the Effects of Obesity on Cancer Immunotherapy Outcomes in Renal Cancer: What Do We Really Know?

Frontiers in Immunology, 2021
Obesity has reached global epidemic proportions and its effects on interactions between the immune system and malignancies, particularly as related to cancer immunotherapy outcomes, have come under increasing scrutiny.
Kristine I. Farag, Amani Makkouk, Lyse A. Norian, Lyse A. Norian, Lyse A. Norian   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source