Results 181 to 190 of about 6,225,903 (287)

Oncometabolites in renal cancer

Nature Reviews Nephrology, 2019
Cissy Yong, G. Stewart, C. Frezza
semanticscholar   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Renal Granuloma Distinct From the Renal Pelvis Following Bacillus Calmette-Guérin Treatment for Bladder Cancer: A Case Report. [PDF]

IJU Case Rep
Oka R, Goto Y, Mikami K, Kato H, Wakai K, Hou K, Araki K, Fujino T, Yamazaki K, Naya Y.   +9 more
europepmc   +1 more source

Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA.

Cancer Cell, 2016
Le Qu, Jin Ding, Cheng Chen, Zhenjie Wu, Bing Liu, Yi Gao, Wei Chen, Feng Liu, Wen Sun, Xiaofeng Li, Xue Wang, Yue Wang, Zhen-Yu Xu, Li Gao, Qing Yang, Bin Xu, Yao-ming Li, Zi-yu Fang, Z. Xu, Y. Bao, Deng-shuang Wu, X. Miao, Hai-Yang Sun, Yinghao Sun, Hong-Yang Wang, Lin-hui Wang   +25 more
semanticscholar   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Causal association between socioeconomic disparities and tumors of the urinary system: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Chen WW, Wu B, Wen X.
europepmc   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Adverse Renal Outcomes in Patients With Mesothelioma-A Territory-Wide Real-World Data. [PDF]

Cancer Med
Kwok WC, Ho JCM, Leung ISH, Yap DYH.
europepmc   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Plasma Levels of Aromatase, Cathepsin S and Matrix Metalloproteinase 1 in Renal Cell Carcinomas: Implications for Tumor Progression and Diagnostic Value. [PDF]

Cancers (Basel)
Guszcz T, Sankiewicz A, Gorodkiewicz E.
europepmc   +1 more source