Results 21 to 30 of about 1,560 (139)

Estudios preclínicos de seis moléculas que interfieren en el ensamblaje de la cápside del VIH como posibles fármacos antirretrovirales [PDF]

, 2023
La cápside del VIH está formada por el ensamblaje de una única proteína viral (CA), que desempeña un papel esencial en las primeras y últimas etapas de la infección. El ensamblaje correcto de la cápside es necesario para la infectividad del VIH.
Guillon, Christophe, Artía, Zoraima, Randall, Lía, Segovia, Ana Clara, Corvo, Ileana, Granzella, Maximiliano, Robert, Xavier, Álvarez, Guzmán   +7 more
core  

Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV‐1

Scientifica, Volume 2013, Issue 1, 2013., 2013
Type I interferon (IFN‐I) play a critical role in the innate immune response against viral infections. They actively participate in antiviral immunity by inducing molecular mechanisms of viral restriction and by limiting the spread of the infection, but they also orchestrate the initial phases of the adaptive immune response and influence the quality ...
Adriano Boasso, G. Chen, M. Clementi
wiley   +1 more source

Puesta a punto de un ensayo de multimerización in vitro de la proteína de la cápside del Virus de la Inmunodeficiencia Humana [PDF]

, 2023
El virus de la Inmunodeficiencia Humana (VIH) es un retrovirus que afecta el sistema inmunitario debilitando las defensas del huésped, y puede evolucionar eventualmente al Síndrome de Inmunodeficiencia Adquirida (SIDA).
Randall, Lía, Artía, Zoraima, Alvarez, Guzmán, Corvo, Ileana, Granzella, Maximiliano   +4 more
core   +2 more sources

An Overview on the Field of Micro‐ and Nanotechnologies for Synthetic Peptide‐Based Vaccines

Journal of Drug Delivery, Volume 2011, Issue 1, 2011., 2011
The development of synthetic peptide‐based vaccines has many advantages in comparison with vaccines based on live attenuated organisms, inactivated or killed organism, or toxins. Peptide‐based vaccines cannot revert to a virulent form, allow a better conservation, and are produced more easily and safely.
Aiala Salvador, Manoli Igartua, Rosa Maria Hernández, José Luis Pedraz, Sanyog Jain   +4 more
wiley   +1 more source

Novel Phenazine 5,10‐Dioxides Release •OH in Simulated Hypoxia and Induce Reduction of Tumour Volume In Vivo

International Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
Phenazine 5,10‐dioxides (PDOs) are a new class of bioreductive cytotoxins, which could act towards tumours containing hypoxic regions. The PDOs selective‐hypoxic bioreduction was probed in vitro; however, the mechanism of action has not been completely explained. Besides, PDOs in vivo antitumour activities have not been demonstrated hitherto.
María L. Lavaggi, Mauricio Cabrera, Cristina Pintos, Carolina Arredondo, Gisela Pachón, Jorge Rodríguez, Stella Raymondo, José Pedro Pacheco, Marta Cascante, Claudio Olea-Azar, Adela López de Ceráin, Antonio Monge, Hugo Cerecetto, Mercedes González, P. Cos   +14 more
wiley   +1 more source

GENETIC VARIABILITY OF PRSV-p ISOLATES FROM PAPAYO IN THE CENTRAL ZONE OF THE STATE OF VERACRUZ, MEXICO

Tropical and Subtropical Agroecosystems, 2022
Background: The Potyvirus Papaya ringspot virus type P (PRSV-p) causes the papaya (Carica papaya L.) ringspot disease, which causes damage to the plantations of this crop.
David Sósol-Reyes, Juan A. Villanueva-Jiménez, Francisco Osorio-Acosta, Norma Flores-Estévez, Juan C. Noa-Carrazana   +4 more
doaj   +1 more source

Gene Therapy for HIV Infections: Intracellular Immunization

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 10, Issue 4, Page 307-312, 1999., 1999
Despite significant advances in the treatment of human immunodeficiency virus (HIV) infection in the past 10 years, it remains an incurable disease. The inability of traditional drug‐based therapies to inhibit HIV replication effectively for extended periods of time has stimulated intense research to develop novel approaches for this disease.
Alain Piché
wiley   +1 more source

Prevalencia de cinco virus de ARN en tubérculos-semilla de papa cultivados en Antioquia (Colombia)

Biotecnología en el Sector Agropecuario y Agroindustrial, 2022
La papa (Solanum tuberosum) es uno de los productos agrícolas con mayor demanda interna en Colombia. Este cultivo es afectado por un complejo de virus que reduce los rendimientos y la calidad de los tubérculos-semilla.
Yuliana Marcela Gallo García, Andrea Sierra Mejia, Pablo Andrés Gutiérrez Sánchez, Mauricio Alejandro Marín Montoya   +3 more
doaj   +1 more source

Pathogenesis of HSV and CMV Infections in Pregnancy

Infectious Diseases in Obstetrics and Gynecology, Volume 5, Issue 2, Page 133-141, 1997., 1997
Human herpesvirus (HHSV) and human cytomegalovirus (HCMV) infections during pregnancy are a major concern of public health because of the risk for severe sequelae for the fetuses and the neonates and because primary infections, reinfections and reactivations can be asymptomatic. The risk for neonatal herpes is mostly congenital, while the risk for HCMV
Myriam Askienazy-Elbhar, Christophe Sifer   +1 more
wiley   +1 more source

Incidencia de potyvirus y caracterización molecular de PVY en regiones productoras de papa (Solanum tuberosum L.) de Colombia

Revista Colombiana de Biotecnología, 2011
Incidence of potyvirus and molecular characterization of PVY in potato (Solanum tuberosum L.) growing regions of ColombiaTítulo corto: Incidencia de potyvirus en cultivos de papa de Colombia ResumenLos problemas virales reducen los rendimientos y la ...
José Miguel Cotes, José Fernando Gil, Mauricio Marín   +2 more
doaj   +2 more sources