Results 51 to 60 of about 225,356 (198)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Características químicas do solo em área de pastagem nativa recém queimada no Pantanal arenoso, MS. [PDF]
, 2011 Estudou-se as alterações nas características químicas do solo sob pastagem nativa, no Pantanal Mato-Grossense, 15 dias após a queima. Foram demarcadas parcelas de 100x40m em área de savana gramíneo-lenhosa onde predominava o capim-carona (Elyonurus ...
FERNANDES, A. H. B. M., FERNANDES, F. A.
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Relações entre bases trocáveis no solo em sistema orgânico de bananeiras sob cultivo de coberturas vegetais vivas. [PDF]
, 2012 As interações entre nutrientes na cultura da banana são importantes, principalmente as relações entre as bases potássio (K), cálcio (Ca) e magnésio (Mg).
BORGES, A. L. +2 more
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Caracterização dos solos de São José do Norte, Tavares e Mostardas-RS. [PDF]
, 2014 bitstream/item/41366/1/Sao-Jose-do-Norte.pdf; bitstream/item/41367/1/mapa-mostarda-capacidade-de-uso.pdf; bitstream/item/41368/1/mapa-mostarda-geomorfologia-e-solos.pdf; bitstream/item/41369/1/mapa-mostarda-solos.pdf; bitstream/item/41370/1/mapa ...
CUNHA, N. G. da
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Caracterização e classificação dos solos do Campo Experimental do Cerrado da Embrapa Amapá, Estado do Amapá. [PDF]
, 2016 bitstream/item/63154/1/Oriental-Doc43 ...
BARRETO, W. de O. +3 more
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source