Results 61 to 70 of about 343,141 (245)

The Role of Self-Collection by Vaginal Lavage for the Detection of HPV and High-Grade Intraepithelial Neoplasia [PDF]

open access: yes, 2017
The Role of Self-Collection by Vaginal Lavage for the Detection of HPV and High-Grade Intraepithelial NeoplasiaObjective: To compare the results of cervical cytology and high-risk HPV tests using samples obtained using two different collection modalities
Antoniazzi, Márcio   +7 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Prevenção do câncer cervical

open access: yesDST, 2010
Introdução: o câncer do colo uterino é conhecido como uma das causas mais frequentes de óbito na população feminina em todo o mundo. A infecção persistente por papilomavírus humano (HPV) é o principal fator de risco para o câncer cervical e suas lesões ...
Márcia Elena Z. Bringhenti   +3 more
doaj  

Prevenção de lesões epiteliais de colo uterino em gestantes atendidas no hospital universitário de Santa Maria [PDF]

open access: yes, 2014
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.O câncer do colo uterino, também chamado de cervical ...
Bonfanti, Gabriela   +3 more
core  

Presence of cells of the cervical transicional zone in cervicovaginal smears in women older than 40 years old [PDF]

open access: yes, 2011
OBJETIVO: avaliar a frequência de células da junção escamo-colunar (JEC) em esfregaços cérvico-vaginais de mulheres com 40 anos ou mais. MÉTODOS: foi realizado um estudo retrospectivo, com revisão de 24.316 laudos colpocitológicos realizados no período ...
BARBOSA, Ricardo Luís   +3 more
core   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Cervical cancer screening by cytology and the burden of epithelial abnormalities in low resource settings: a tertiary-center 42-year study

open access: yesBMC Women's Health
Background Cytological screening remains a high-impact practice, particularly in low-resource settings, for preventing cervical cancer. The examination of screening practices over time and the prevalence of epithelial abnormalities have not been ...
Sahar Ezzelarab   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Tratamento de infecção subclínicas pelo pepilomavirus humano (HPV) no colo uterino

open access: yesDST, 1998
O tratamento da forma subclinica de infecção pelo papUomavirus humano (HPV) tem sido alvo de controvérsia . Trata-se de infocção muito prevalente e com forte associação ao cãncer cêrvico-uterino.
Fábio Russumano   +5 more
doaj  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

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