Results 81 to 90 of about 343,141 (245)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Rastreamento de câncer de colo uterino em São Paulo

DST, 2003
Introdução: Nas últimas décadas, o papel do HPV tem sido intensamente estudado devido à sua íntima associação com a gênese de uma série de car­ cinomas; principalmente com relação aos do trato genital feminino.
Cecília M Roteli-Martins, Adhemar L Filho, Janice O Galvane, Edson Z Martinez, Celso di Loreto, Maria Lúcia Utagawa, Fernanda C Arlindo, Sonia Maria M Pereira, Laura M Martins, Janaína E Pittoli, Sonici F Figueiredo, Luciana S Aguiar, Marina Y S Maeda, Kari J Syrjãnen   +13 more
doaj  

Clinico-epidemiological aspects associated with penile cancer [PDF]

, 2010
O objetivo desta revisão bibliográfica foi descrever a epidemiologia, o comportamento biológico dos tumores e os fatores de risco para o câncer de pênis, como a infecção pelo HPV.
CRUZ, Aparecido Divino da, PAULA, Adriano Augusto Peclat de, PAULA, Leonardo Barcelos de, REIS, Angela Adamski da Silva, SADDI, Vera Aparecida   +4 more
core   +2 more sources

Reprogramming Tumor Cell Death via Processing Natural Drug to Carbon Dots Overcomes Collagen Barrier and Activates Antitumor Immunity

Advanced Functional Materials, EarlyView.
A traditional Chinese medicine‐derived carbon dots nanoplatform reprograms tumor cell death from apoptosis to necroptosis, dismantling therapy‐induced collagen barriers and promoting immunogenic death. pH‐responsive hydrogel assembled from carbon dots for localized delivery, this strategy suppresses primary tumors and metastasis, offering a new ...
Zekun Yan, Hongwei Cheng, Yupeng Liu, Wenfeng Xu, Quansheng Cheng, Lingyun Li, Xue Wu, Yingqi Liang, Jing Zhao, Gang Liu, Shaoping Li, Songnan Qu   +11 more
wiley   +1 more source

Selected Risk Factors for Cervical Cancer and Barriers to Cervical Cancer Screening

Acta Medica Martiniana, 2014
The article provides a review of literature on risk factors and cofactors for cervical cancer and barriers to cervical cancer screening. Cofactors of cervical cancer are risk factors that contribute to the development of cervical cancer but are not able ...
V. Szaboova, V. Svlhrova, V. Hudeckova
doaj   +1 more source

Loop electrosurgical excision procedure and colposcopic localization of the atypical cervical epithelium [PDF]

, 2001
Purpose: to evaluate the histopathologic results of cone specimens of patients undergoing loop electrosurgical excision procedure (LEEP) and their relationship with the localization of the lesion.
Baracat, Edmund Chada, Cardoso, Maria Silvana, Focchi, José, Lima, Geraldo Rodrigues, Ribalta, Julisa Chamorro Lascasas, Taha, Nabiha Saadi Abrahão   +5 more
core   +2 more sources

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

O Enfermeiro na Prevenção do Câncer Cérvicouterino e de Mama [PDF]

, 2014
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.O câncer cérvicouterino é a terceira neoplasia maligna
Ahmann, Laura Cristina, Araldi, Amanda, Berté, Caroline, Boaretto, Flávia, Bratti, Bruna, Caldeira, Sebastião, Deves, Poliana, Faquini, Karina, Guisso, Ana Carolina, Junges, Juliana, Kovaleski, Adriana, Lopes, Pecy, Mandrick, Anna, Oliveira, Danuza, Oliveira, Elis, Seimetz, Gabriela, Silva, Jessica, Valandro, Ana Paula, Xavier, Priscila   +18 more
core  

Historical analysis of the Brazilian cervical cancer screening program from 2006 to 2013: a time for reflection [PDF]

, 2015
BACKGROUND: The Cervical Cancer Database of the Brazilian National Health Service (SISCOLO) contains information regarding all cervical cytological tests and, if properly explored, can be used as a tool for monitoring and managing the cervical cancer ...
A Mathew, AA Renshaw, AdA Pinho, Adhemar Longatto-Filho, CZ Azara, Céline Pinheiro, DB Vale, DD Davey, DSMd Silva, EJC Manrique, EL Franco, GM Eversole, HGd Freitas, HJ Kim, J Ferlay, JF Nygard, José Humberto Fregnani, L Madlensky, LC Zeferino, LSC Thuler, Luiz Carlos Zeferino, Marcia Edilaine Lopes Consolaro, P Adab, R Franco, RA Freitas, Ricardo Filipe Alves Costa, RM Dufloth, S Correa Mda, VR Girianelli   +28 more
core   +3 more sources