Results 201 to 210 of about 10,776,501 (260)

Zn2+‐Driven Self‐Amplifying Nanoplatform Enables Cascade Photothermal–Gene Therapy via Mitochondrial Disruption

VIEW, EarlyView.
A Zn2+‐activated nanoplatform enables self‐amplifying photothermal–gene therapy by disrupting mitochondria and releasing siRNA, creating a feedback loop that sensitizes tumor cells and enhances ablation in vitro and in vivo. This metal ion‐driven strategy offers a new approach for cascade‐amplified nanotherapeutics. ABSTRACT The therapeutic efficacy of
Zhi Li, Yuhong Chen, Youfei Zhang, Luzhen Huai, Xingzhou Zhu, Xue Mo, Jiahao Wang, Kui Zeng, Jie Wang   +8 more
wiley   +1 more source

Treatment Summary and Care Plan for Breast Cancer Survivors: acceptability and feasibility study. [PDF]

Rev Lat Am Enfermagem
Matsubara MDGS, Makdissi FBA, Elias S, Bergerot CD, Ashing KT, Domenico EBL.   +5 more
europepmc   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Care strategies for people with cancer in light of Uncertainty in Illness Theory. [PDF]

Rev Bras Enferm
Silveira JM, Spagnolo LML, Rangel RF, Cordeiro FR, Schwartz E, Oliveira TB, Stübe M, Oliveira CB.   +7 more
europepmc   +1 more source

Clinical Relevance of the SOUND and INSEMA Trials in Women With Early Breast Cancer in Australia and New Zealand

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Axillary surgery in breast cancer has undergone progressive de‐escalation. The recent Sentinel Node versus Observation after Axillary Ultrasound (SOUND) and Intergroup Sentinel Mamma (INSEMA) trials have demonstrated that sentinel lymph node biopsy may be safely omitted in selected patients. This study aimed to evaluate the clinical
Matea Dominkovic, Kerry Hitos, Wei Wang, T. Michael Hughes, James French, Nicholas Ngui   +5 more
wiley   +1 more source

Spindle Cell Lesions of the Breast: A 12‐Year Experience

ANZ Journal of Surgery, EarlyView.
This 12‐year, single‐centre study examined 30 core‐biopsy‐diagnosed breast spindle cell lesions (BrSCL), classified as atypical (ASCL, n = 10) or bland (BSCL, n = 20). Following excision, 80% of ASCLs proved malignant, comprising sarcoma, malignant phyllodes tumour and metaplastic carcinoma.
Shalvin Jassal, Wesley Tjang, Shaun Monagle, Michael Law, Justin James   +4 more
wiley   +1 more source

[Nursing consultations in primary health care in Brazil: distribution and productivity in the management of chronic noncommunicable diseasesConsultas atendidas por personal de enfermería en la atención primaria de salud en Brasil: distribución y productividad en las consultas relativas a enfermedades crónicas no transmisibles]. [PDF]

Rev Panam Salud Publica
Mendes IAC, de Almeida EWS, Silva ÍR, de Andrade EMLR, Bernardes RM, Almeida RGDS, Siqueira EF, da Silva MCN, de Godoy S.   +8 more
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

[Clinical coordination and strengthening of primary care for cancer diagnosis in Latin America: a scoping reviewCoordenação clínica e fortalecimento da atenção primária no diagnóstico do câncer na América Latina: revisão de escopo]. [PDF]

Rev Panam Salud Publica
Luer-Aguila R, Oliver-Anglès A, Vázquez ML, Vargas I.   +3 more
europepmc   +1 more source