Results 21 to 30 of about 805,425 (200)

Abdómen agudo: volvo do cólon transverso.

Acta Médica Portuguesa, 2011
Volvulus of the transverse colon continues to be a rare medical problem in the bibliographic medical revisions of large bowel obstructions (1%), being frequently excluded of the differential diagnosis.
Sónia Palma, João Leitão, Helena Lopes da Silva, Isabel Távora   +3 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Preparo intra-operatório do cólon

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Apresentar nossa experiência com o preparo intra-operatório do cólon no tratamento de pacientes com obstrução neoplásica do cólon esquerdo. MÉTODO: Vinte e três pacientes com obstrução neoplásica do cólon esquerdo foram operados no Hospital de ...
Alexandre Cruz Henriques, Sérgio Pezzolo, Marise Gomes, Carlos Alberto Godinho, Viviane Aparecida Sotto Bazalia, Manlio Basilio Speranzini   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Influência da peritonite sobre a síntese de colágeno em anastomoses do cólon distal: estudo experimental em ratos

Acta Cirúrgica Brasileira, 2000
Com o objetivo de verificar a relação entre a concentração de colágeno e a capacidade de suportar pressão em anastomoses de cólon quando existe peritonite, utilizaram-se 40 ratos machos, Wistar-TECPAR, com idade média de 120 dias e peso médio de 302 g ...
Maria de Lourdes Pessole Biondo-Simões, Fernando Hintz Greca, Agostinho Bryk Junior, Maria Cláudia Gomes Komatsu, Fabiano de Oliveira Bittencourt, Letícia Maria Greca   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A suppository-base-matrix tablet for time-dependent colon-specific delivery system

Brazilian Journal of Pharmaceutical Sciences, 2014
Our research has focused on the main design features and release performances of time-dependent colon-specific (TDCS) delivery tablets, which relies on the relative constancy that is observed in the small intestinal transit time of dosage forms.
Meijuan Zou, Caixia Wang, Xuezhu Zhang, Tao Xu, Jiarong Han, Xiao Zhang, Gang Cheng   +6 more
doaj   +1 more source

Nubes bajo la cumbre: posible huella de Rerum familiarum, IV, 1 de Petrarca en la Carta para Arias Montano de Francisco de Aldana, y en la Elegía VI de Fernando de Herrera

Criticón, 2023
In his epistle of Rerum familiarum libri IV, 1, Petrarca narrates his ascension to Mount Ventoso. He describes various natural elements (such as the mountain, the earth, the sea) and when he reaches te summit he alludes to «nubes erant sub pedibus».
Isabel Colón Calderón
doaj   +1 more source