Results 31 to 40 of about 808,601 (248)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Preparo intra-operatório do cólon
Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: Apresentar nossa experiência com o preparo intra-operatório do cólon no tratamento de pacientes com obstrução neoplásica do cólon esquerdo. MÉTODO: Vinte e três pacientes com obstrução neoplásica do cólon esquerdo foram operados no Hospital de ...
Alexandre Cruz Henriques +5 more
doaj +1 more source
Watershed Colonialism and Popular Geographies of North American Rivers
Open Rivers, 2017 Rivers have long been the subject and vehicle for compelling stories. As physical features that tie natural and human history, rivers in narratives have hidden as much as they’ve revealed by naturalizing cultural practices and human values...
Sigma Colon
doaj +1 more source
Sustentabilidade em Debate, 2018 “Slow Violence” is the key concept in the ecocritical thought of Rob Nixon and it has been an inspiration for the documentary Beyond Fordlândia. Slow Violence is defined as “a violence that occurs gradually and out of sight, a violence of delayed ...
Marcos Cólon
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The effect of benzalkonium chloride on the serosa surface of colon rats, diluted in different solvents [PDF]
, 2003 Objetivo: Estudar o efeito do cloreto de benzalconeo a 0,1 por cento diluido em diferentes solventes, aplicado na superficie serosa do colon sigmoide de ratos. Metodo: Utilizou-se 225 ratos machos, Wistar, com 90 dias de vida, subdivididos em 5 grupos de
Gerardi Filho, Vicente Antonio
core +1 more source
A suppository-base-matrix tablet for time-dependent colon-specific delivery system
Brazilian Journal of Pharmaceutical Sciences, 2014 Our research has focused on the main design features and release performances of time-dependent colon-specific (TDCS) delivery tablets, which relies on the relative constancy that is observed in the small intestinal transit time of dosage forms.
Meijuan Zou +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Acta Cirúrgica Brasileira, 2000 Com o objetivo de verificar a relação entre a concentração de colágeno e a capacidade de suportar pressão em anastomoses de cólon quando existe peritonite, utilizaram-se 40 ratos machos, Wistar-TECPAR, com idade média de 120 dias e peso médio de 302 g ...
Maria de Lourdes Pessole Biondo-Simões +5 more
doaj +1 more source