Results 31 to 40 of about 799,385 (200)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Preparo intra-operatório do cólon
Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: Apresentar nossa experiência com o preparo intra-operatório do cólon no tratamento de pacientes com obstrução neoplásica do cólon esquerdo. MÉTODO: Vinte e três pacientes com obstrução neoplásica do cólon esquerdo foram operados no Hospital de ...
Alexandre Cruz Henriques +5 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Watershed Colonialism and Popular Geographies of North American Rivers
Open Rivers, 2017 Rivers have long been the subject and vehicle for compelling stories. As physical features that tie natural and human history, rivers in narratives have hidden as much as they’ve revealed by naturalizing cultural practices and human values...
Sigma Colon
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Acta Cirúrgica Brasileira, 2000 Com o objetivo de verificar a relação entre a concentração de colágeno e a capacidade de suportar pressão em anastomoses de cólon quando existe peritonite, utilizaram-se 40 ratos machos, Wistar-TECPAR, com idade média de 120 dias e peso médio de 302 g ...
Maria de Lourdes Pessole Biondo-Simões +5 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Revista Derecho del Estado, 2021 Para la teoría constitucional hay dos preguntas claves que surgen en cualquier discusión acerca de la creación de nuevas constituciones. Primero, ¿qué mecanismo debe utilizarse para el ejercicio del poder constituyente?
Joel Colón-Ríos
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A suppository-base-matrix tablet for time-dependent colon-specific delivery system
Brazilian Journal of Pharmaceutical Sciences, 2014 Our research has focused on the main design features and release performances of time-dependent colon-specific (TDCS) delivery tablets, which relies on the relative constancy that is observed in the small intestinal transit time of dosage forms.
Meijuan Zou +6 more
doaj +1 more source