Results 81 to 90 of about 233,851 (293)
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Advanced Science, EarlyView.Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source
Dolor ocular crónico neuropático en Oftalmología [PDF]
, 2016 El dolor ocular crónico neuropático es, a día de hoy, una entidad ampliamente desconocida, cuya fisiopatología resulta aún incierta. Esto hace que quienes sufren esta incapacitante dolencia sean incomprendidos por la comunidad médica, que aún no ha ...
Nevares Herrero, Marina
core
Atypical presentation of pellucid marginal degeneration: case report [PDF]
, 2005 The authors report an unusual clinical presentation of pellucid marginal degeneration with 360º peripheral corneal thinning diagnosed in a younger male patient. We discuss the findings of topographic maps, ultrasound pachymetry and the proposed treatment.
Machado, Renato +4 more
core +3 more sources
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Amniotic membrane transplantation for severe acute cases of chemical ocular burn and Stevens-Johnson syndrome [PDF]
, 2009 PURPOSE: To study the therapeutic potential of amniotic membrane transplantation in cases of severe acute chemical ocular burn and Stevens-Johnson syndrome.
Barros, Sabrina Leite de +4 more
core +2 more sources
Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety
Advanced Science, EarlyView.This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi +15 more
wiley +1 more source
Trasplante de córnea: retos y perspectivas
Universidad Médica Pinareña, 2014 Introducción: los trasplantes de órganos son reconocidos a nivel internacional como la opción terapéutica por excelencia para los pacientes con enfermedades crónicas degenerativas y constituyen el único tratamiento capaz de rehabilitarlos integralmente y
Martínez Noda Sandra María +3 more
doaj +2 more sources
Estudio retrospectivo sobre cambios en la morfología corneal tras crosslinking [PDF]
, 2011 S'ha realitzat un estudi retrospectiu de 41 casos clínics de queratocon mesurant les variables abans i després de la intervenció (al primer mes postoperatori, als 3 mesos i als 6 mesos).
Centre d'Oftalmologia Barraquer +4 more
core +1 more source
Advanced Science, EarlyView.This review presents a comprehensive overview of FET‐based visual neuromorphic systems, covering their semiconductor materials, core device architectures, and operating mechanisms. It further reviews their implementation in emulating biological visual functions, addresses current technological challenges, and outlines future development directions. The
Liu Yaqian +11 more
wiley +1 more source