Results 61 to 70 of about 748,226 (258)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Catalysis of C-N Coupling on High-Entropy Alloys
, 2023 Catalyzing carbon-nitrogen (C-N) coupling using small abundant nitrogenous molecules is of growing interest to lessen the environmental impact of the industrial process.
Mads Kastrup, Plenge +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Selenophene-containing heterotriacenes by a C–Se coupling/cyclization reaction
Beilstein Journal of Organic Chemistry, 2019 A new novel family of tricyclic sulfur and/or selenium-containing heterotriacenes 2–4 with an increasing number of selenium (Se) atoms is presented. The heterotriacene derivatives were synthesized in multistep synthetic routes and the crucial cyclization
Pierre-Olivier Schwartz +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2023 Paired redox-neutral electrolysis offers an attractive green platform for organic synthesis by avoiding sacrificial oxidants and reductants. Here, we report the electro/Ni dual-catalyzed redox-neutral C(sp3)−C(sp2) cross-coupling reactions between ...
Daniel, Ess +3 more
core +1 more source
Nano ResearchPhoto-reforming methanol into valuable chemicals represents an energetically sustainable alternative to conventional thermal catalysis, yet controlling-specific C–C coupling way still remains elusive.
Yixin Song +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2014 Funding: UK Engineering and Physical Sciences Research Council (EPSRC)As part of a programme aimed at exploiting lignin as a chemical feedstock for less oxygenated fine chemicals, several catalytic C-C bond forming reactions utilising guaiacol imidazole ...
Clarke, Matthew L. +2 more
core +1 more source
, 2020 Cross-coupling of two alkyl fragments is an efficient method to produce organic molecules rich in sp3-hydridized carbon centers, which are attractive candidate compounds in drug discovery.
Srikrishna, Bera, Runze, Mao, Xile, Hu
core +1 more source