Recent Advances on Synthetic Methodology Merging C–H Functionalization and C–C Cleavage
Molecules, 2020 The functionalization of C–H bonds has become a major thread of research in organic synthesis that can be assessed from different angles, for instance depending on the type of catalyst employed or the overall transformation that is carried out.
Hamid Azizollahi +1 more
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Carboxylate-Assisted C(sp^3)–H Activation in Olefin Metathesis-Relevant Ruthenium Complexes [PDF]
, 2014 The mechanism of C–H activation at metathesis-relevant ruthenium(II) benzylidene complexes was studied both experimentally and computationally. Synthesis of a ruthenium dicarboxylate at a low temperature allowed for direct observation of the C–H ...
Cannon, Jeffrey S. +6 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard +8 more
wiley +1 more source
Catalytic Asymmetric Functionalization of Inert Bonds and Synthesis of Bioactive Natural Products
CHIMIA, 2011 The direct and enantioselective functionalization of inert bonds such as carbon–hydrogen and carbon–carbon is an emerging tool towards more sustainable and efficient synthetic methods.
Nicolai Cramer
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Computational exploration of the reaction mechanism of the Cu+-catalysed synthesis of indoles from N-aryl enaminones [PDF]
Royal Society Open Science, 2016 We have studied the role of Cu+-phenantroline as a catalyst in the cyclization of N-aryl-enaminones using density-functional theory computations. The catalyst was found to bind the substrate upon deprotonation of its eneaminone, and to dramatically ...
Carlos E. P. Bernardo, Pedro J. Silva
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Scope and Mechanistic Study of the Ruthenium-Catalyzed \u3cem\u3eortho\u3c/em\u3e-C−H Bond Activation and Cyclization Reactions of Arylamines with Terminal Alkynes [PDF]
, 2005 The cationic ruthenium hydride complex [(PCy3)2(CO)(CH3CN)2RuH]+BF4- was found to be a highly effective catalyst for the C−H bond activation reaction of arylamines and terminal alkynes.
Yi, Chae S., Yun, Young
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C−H Bond Activation by Dicationic Platinum(II) Complexes [PDF]
, 2007 Double protonolysis of diimine platinum dimethyls [(N-N)PtMe_2] (N-N ═ ArNC(Me)C(Me) ═ NAr) generates dicationic Pt(II) complexes that can activate a variety of C−H bonds, liberating 1 equiv of acid and forming organoplatinum species that are moderately ...
Bercaw, John E. +3 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
Cobalt-catalyzed nucleophilic addition of the allylic C(sp3)–H bond of simple alkenes to ketones
Beilstein Journal of Organic Chemistry, 2018 We herein describe a cobalt/Xantphos-catalyzed regioselective addition of simple alkenes to acetophenone derivatives, affording branched homoallylic alcohols in high yields with perfect branch selectivities.
Tsuyoshi Mita +3 more
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Phenylacetylene and Carbon Dioxide Activation by an Organometallic Samarium Complex
Inorganics, 2018 Small molecule activation is a topic of growing importance and the use of low-valent f-elements to perform these reactions is nowadays well established.
Violaine Goudy +6 more
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