Results 51 to 60 of about 31,239,114 (260)

Natural Product Synthesis by C-H Activation

, 2018
The widespread use of transition-metal-mediated C-H bond activation has altered the field of organic synthesis. Notwithstanding the immense effect this strategy has had on classical organic reactions, the applications of this methodology extend further ...
MAITI, D, SINHA, SK, ZANONI, G
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Rhodium(III)-Catalyzed Enantioselective Coupling of Indoles and 7-Azabenzonorbornadienes by C-H Activation/Desymmetrization

, 2019
Chiral rhodium(III) cyclopentadienyl catalysts ((CpRhIII)-Rh-X) play significant roles in asymmetric arene C-H activation. Rh/Ir-catalyzed couplings of arenes and strained rings have been well-studied, but they have been limited to racemic systems ...
Yang, Xifa, Zheng, Guangfan, Li, Xingwei
core   +1 more source

Ligand Accelerated Hydrogen Isotope Exchange: Switching C-H Activation from Functionalization Towards C-D Bond Formation [PDF]

, 2023
Hydrogen isotope exchange (HIE) has emerged as a unique strategy for labelling, affording plenty of deuterated chemicals with varieties in patterns.
Jianfei, Bai, Bencan, Tang, Dawei, Xu, Jiakai, Lu, Zhi-Jiang, Jiang, Zhanghua, Gao, Jia, Chen   +6 more
core   +2 more sources

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Metal Nanoparticles as Sustainable Tools for C–N Bond Formation via C–H Activation

Molecules, 2021
The design of highly active metal nanoparticles to be employed as efficient heterogeneous catalysts is a key tool for the construction of complex organic molecules and the minimization of their environmental costs.
Federica Valentini, Oriana Piermatti, Luigi Vaccaro   +2 more
doaj   +1 more source

Deuteration of Arenes via Pd-Catalyzed C–H Activation – A Lesson in Nondirected C–H Activation, Isotopic Labelling and NMR Characterization [PDF]

Isotopic labelling is an important tool in medicinal research, metabolomics, and for understanding reaction mechanisms. In this context, transition metal catalyzed C–H activation has emerged as a key technology for deuterium incorporation via hydrogen ...
Fritz, Deufel, Manuel, van Gemmeren
core   +2 more sources

C−H Bond Activation by Iridium(III) and Iridium(IV) Oxo Complexes [PDF]

, 2023
Oxidation of an iridium(III) oxo precursor enabled the structural, spectroscopic, and quantum-chemical characterization of the first well-defined iridium(IV) oxo complex.
Verplancke, H., Schneider, S., Fitterer, A., Holthausen, M.C., Delony, D., de Bruin, B., Tepaske, M.A., Neben, M.C., Holthausen, Max C., Delony, Daniel, Neben, Marc C., Verplancke, Henrdik, Tepaske, Martijn Alexander, Fitterer, Arnd, de Bruin, Bas, Schneider, Sven   +15 more
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source