Results 191 to 200 of about 21,387,745 (369)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Generation of mode-locked pulses based on D-shaped fiber with CdTe as a saturable absorber in the C-band region. [PDF]
Ahmad H, Mansor NH, Reduan SA, Ramli R.
europepmc +1 more source
Physical, dielectric, and C band microwave scattering properties of first‐year sea ice during advanced melt [PDF]
Randall K. Scharien +4 more
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Deuterated Polycyclic Aromatic Hydrocarbons in the Interstellar Medium: The Aliphatic C--D Band Strengths [PDF]
Xuejuan Yang, Aigen Li
openalex +1 more source
The L-/C-band feed design for the DSS 14 70-meter antenna (Phobos mission) [PDF]
A dual-frequency (1.668 and 5.01 GHz) feed was designed for the Deep Space Station (DSS) 14 70-m antenna to support the Soviet Phobos Mission. This antenna system was capable of supporting telemetry, two-way Doppler, and very long baseline interferometry
Reilly, H. F., Jr., Stanton, P. H.
core +1 more source

