Interleukin‐1 ‐induced expression of nitric oxide synthase in insulin‐producing cells is preceded by c‐fos induction and depends on gene transcription and protein synthesis [PDF]
Décio L. Eizirik+2 more
openalex +1 more source
Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu+13 more
wiley +1 more source
Summary: Fish oil supplements (FOS) are known to alter circulating levels of polyunsaturated fatty acids (PUFAs) but in a heterogeneous manner across individuals. These varied responses may result from unidentified gene-FOS interactions.
Susan Adanna Ihejirika+5 more
doaj
Calcium Induction of the mRNAs for Prolactin and c-fos Is Independent of Protein Kinase C Activity
Sudip K. Bandyopadhyay, C Bancroft
openalex +1 more source
Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation [PDF]
Gary Glenn, Walter Eckhart
openalex +1 more source
This study performs dual CRISPR screens in pEPSCs. Fitness screening identifies essential genes for viability, while FACS‐based screening uncovers core pluripotency factors. It highlights FOXH1 as a key regulator that maintains the stem cell state through a dual‐action mechanism: preserving pluripotency by enhancing chromatin accessibility and ...
Peng Su+13 more
wiley +1 more source
No tumor-specific expression levels of protein kinase C isoenzymes and of c-fos in human breast cancer cell cultures [PDF]
Epithelial cells derived from 46 human breast tissue samples of patients suffering from breast cancer have been cultivated. Twenty-five of these cell cultures stemmed from normal and 21 from tumor tissues.
Almendral, A.C.+4 more
core
Highly Crystalline and Oriented Thin Films of Fully Conjugated 3D‐Covalent Organic Frameworks
This work introduces a fully conjugated, 3D covalent organic framework (COF) based on cyclooctatetrathiophene (COTh); the synthesis employs modulated conditions to achieve thin films with high crystallinity. The COTh‐1P COF shows potential for optoelectronic applications, thanks to its π‐conjugated structure, the preferential film orientation, and ...
Ignacio Munoz‐Alonso+9 more
wiley +2 more sources
High‐Density Flexible Neural Implants with Submicron Feedline Resolution
Optimization of microfabrication methods using optical contact lithography (OCL) and electron beam lithography (EBL) enables the fabrication of 64‐channel, high‐density, parylene‐C‐based intracortical implants with submicron feedlines as narrow as 400 and 50 nm, respectively.
Lina Koschinski+10 more
wiley +1 more source