Results 191 to 200 of about 167,917 (334)

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

open access: yesAnnals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang   +10 more
wiley   +1 more source

Exergy and Economic Analysis of Hybrid Mechanical Vapor Compression and Membrane Distillation

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Hybridization of two or more desalination processes has been identified as an attractive option for improved energy efficiency and recovery rate. To appropriately assess the performance enhancement of hybrid desalination systems, an integrated approach for energy, exergy, economic, and environmental investigations should be adopted. This study
Emad Ali, Jamel Orfi
wiley   +1 more source

Influence of Acrylonitrile Content on Processing, Morphology, Thermal Behavior, and Mechanical Properties of PA/NBR Thermoplastic Vulcanizates

open access: yesJournal of Applied Polymer Science, EarlyView.
Influence of acrylonitrile (ACN) content on the processing behavior and morphological development of PA/NBR thermoplastic vulcanizates. Torque‐time profiles, SEM, and SEM/AFM images show that an intermediate ACN level (38%) promotes improved phase dispersion and morphological uniformity, especially with increased processing time, resulting in the most ...
André Luís dos Santos da Silva   +4 more
wiley   +1 more source

Description of the skull, braincase, and dentition of Moschognathus whaitsi (Dinocephalia, Tapinocephalia), and its palaeobiological and behavioral implications

open access: yesThe Anatomical Record, EarlyView.
Abstract A subadult Moschognathus whaitsi from the Eastern Cape Province, South Africa, was scanned using synchrotron radiation X‐ray computed tomography (SRXCT). Its subadult state allowed the cranial bones and teeth to be identified and individually reconstructed in 3D.
Tristen Lafferty   +3 more
wiley   +1 more source

Prefrontal and Subcortical c-Fos Mapping of Reward Responses across Competitive and Social Contexts. [PDF]

open access: yeseNeuro
De Paula Cunha Almeida C   +8 more
europepmc   +1 more source

Morphological variation in atlas and axis of Neotropical spiny rats (Rodentia, Echimyidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract The unique morphologies of the first two cervical vertebrae, the atlas and axis, represent a significant innovation in mammalian evolution. These structures support the weight of the head and enable intricate movements of the head and neck.
Thomas Furtado da Silva Netto   +3 more
wiley   +1 more source

Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine. [PDF]

open access: yesCell Death Discov
Wang K   +10 more
europepmc   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke   +9 more
wiley   +1 more source

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