Results 331 to 340 of about 19,750,598 (378)

Mapping patterns of c-fos expression in the central nervous system after seizure.

Science, 1987
A dramatic and specific induction of c-fos was observed in identifiable neuronal populations in vivo after administration of the convulsant Metrazole. This effect was time- and dose-dependent and was abolished by prior treatment with the anticonvulsant ...
J. Morgan, D. Cohen, J. Hempstead, T. Curran   +3 more
semanticscholar   +1 more source

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling.

Science, 1994
Mice lacking the proto-oncogene c-fos develop the bone disease osteopetrosis. Fos mutant mice were found to have a block in the differentiation of bone-resorbing osteoclasts that was intrinsic to hematopoietic cells.
A. Grigoriadis, Zhaohui Wang, M. Cecchini, W. Hofstetter, R. Felix, H. Fleisch, E. Wagner   +6 more
semanticscholar   +1 more source

Amygdala kindling and c-fos protein(s)☆

Experimental Neurology, 1988
c-fos protein was visualized immunohistochemically in the brains of rats after partial amygdala seizures and generalized amygdala-kindled seizures and in seizure-free amygdala-kindled rats. Four hours following partial amygdala seizures there was a massive induction of c-fos protein in the ipsilateral piriform cortex, entorhinal cortex, and amygdala ...
Mike Dragunow, Harold A. Robertson, George S. Robertson   +2 more
openaire   +3 more sources

Lignocaine–induced convulsion does not induce c–fos protein (c–Fos) in rat hippocampus

Acta Anaesthesiologica Scandinavica, 1994
Recent studies have shown that proto–oncogene c–fos mRNA is induced in the central nervous system by a variety of stimuli including generalised convulsions. In this study, the expression of c–fos protein (c–Fos) following lignocaine–induced convulsions was examined and compared with that following convulsions induced by non–anesthetic convulsants, such
Masahiro Murakawa, Shin-ichi Nakao, M. N. Avramov, Takehiko Adachi, Osamu Yasuhara, Kenjiro Mori, Toshiyuki Arai, Ikuo Tooyama, Hiroshi Kimura, Jiro Kurata   +9 more
openaire   +2 more sources

c-Fos expression during wakefulness and sleep

Neurophysiologie Clinique/Clinical Neurophysiology, 1995
We have recently demonstrated that c-fos expression is strongly induced by both spontaneous and forced wakefulness in many brain regions. c-Fos expression was considerably increased in regions involved in the regulation of arousal states, such as the locus coeruleus (noradrenergic neurons) and the medial preoptic area (non-GABAergic neurons).
POMPEIANO, MARIA, CIRELLI C., ARRIGHI P., TONONI G.   +3 more
openaire   +4 more sources

c-fos antisense RNA blocks expression of c-fos gene in F9 embryonal carcinoma cells

Cell Differentiation and Development, 1988
To study the function of proto-oncogene c-fos, we prepared an antisense plasmid that expresses in mammalian cells c-fos antisense RNA which is complementary to the endogenous c-fos mRNA. Upon transfection into undifferentiated F9 EC cells, the antisense plasmid directed constitutive expression of a large amount of c-fos antisense RNA.
Ben-Zion Levi, John W. Kasik, Keiko Ozato   +2 more
openaire   +3 more sources

c-fos and Growth Control

1986
It is now generally accepted that the normal cellular homologues of retroviral oncogenes, the proto-oncogenes, may have crucial physiological functions in the regulation of cellular proliferation. This hypothesis is strongly supported by the observation that three proto-oncogenes, c-sis, c-erbB and c-fms are part of the cellular growth factor-receptor ...
R. Bravo, R. Müller
openaire   +2 more sources

Protooncogene c-fos as a Transcription Factor

1990
Publisher Summary This chapter discusses the recent advances in the understanding of cellular gene regulation by c-fos—the cellular homolog of the transforming gene (v-fos) of the murine sarcoma viruses FBJ and FBR. The v-fos and c-fos genes are both capable of transforming fibroblasts, although the c-fos gene requires structural alterations.
Robert J. Distel, Bruce M. Spiegelman
openaire   +3 more sources

IGF-I increases C-fos expression in FRTL5 rat thyroid cells by activating the C-fos promoter

Biochemical and Biophysical Research Communications, 1988
We studied the effect of IGF-1 on c-fos mRNA expression in FRTL5 rat thyroid cells. IFG-1, or calf serum, transiently increased c-fos mRNA levels in quiescent FRTL5 cells, with the latter being more potent. This increase was prevented by actinomycin D.
Fred Cox, Fred Cox, Fred Cox, Basil Rapoport, Basil Rapoport, Basil Rapoport, G. Damante, G. Damante, G. Damante   +8 more
openaire   +4 more sources

Regulation of c-Fos and NGF1-A by antidepressant treatments

Synapse, 1997
The influence of antidepressant treatments on the expression of c-Fos and NGF-1A, two immediate early gene (IEG) transcription factors, was examined. Administration of electroconvulsive seizures (ECS), tranylcypromine, or imipramine, three different classes of antidepressants, increased the expression of c-Fos mRNA and immunoreactivity in rat frontal ...
Holly Strausbaugh, Shigeru Morinobu, Ronald S. Duman, Rose Z. Terwilliger   +3 more
openaire   +3 more sources