Results 31 to 40 of about 167,917 (334)
Multiple mechanisms of growth hormone-regulated gene transcription [PDF]
, 2007 Diverse physiological actions of growth hormone (GH) are mediated by changes in gene transcription. Transcription can be regulated at several levels, including post-translational modification of transcription factors, and formation of multiprotein ...
Calinescu, Anda Alexandra +8 more
core +1 more source
Old players with a newly defined function: Fra-1 and c-Fos support growth of human malignant breast tumors by activating membrane biogenesis at the cytoplasm. [PDF]
PLoS ONE, 2013 A shared characteristic of tumor cells is their exacerbated growth. Consequently, tumor cells demand high rates of phospholipid synthesis required for membrane biogenesis to support their growth.
Ruben D Motrich +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2022 The activation of the p53 pathway has been associated with neuronal degeneration in different neurological disorders, including spinal muscular atrophy (SMA) where aberrant expression of p53 drives selective death of motor neurons destined to degenerate.
Jannik M. Buettner +5 more
doaj +1 more source
The function of heterodimeric AP-1 comprised of c-Jun and c-Fos in activin mediated Spemann organizer gene expression. [PDF]
PLoS ONE, 2011 BACKGROUND:Activator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific role of AP-1 in activin signaling has not been elucidated during vertebrate development. METHODOLOGY/PRINCIPAL FINDINGS:We provide
Sung-Young Lee +12 more
doaj +1 more source
Frontiers in Plant Science, 2022 Terpenes serve important functions in enhancing plant thermotolerance. Cinnamomum camphora mainly has eucalyptol (EuL), camphor (CmR), linalool (LnL) and borneol (BeL) chemotypes basing on the uppermost monoterpenes.
Chenyi Xu +15 more
doaj +1 more source
Increased Accuracy to c‐Fos‐Positive Neuron Counting [PDF]
BioMed Research International, 2021 There is not a described method to count the core label of c‐Fos‐positive neurons, avoiding false‐positive and false‐negative results. The aim of this manuscript is to provide guidelines for a secure and accurate method to calculate a threshold to select which core of c‐Fos‐positive neurons marked by immunofluorescence has to be scored.
Wellington José da Silva +3 more
openaire +2 more sources
Cellular & Molecular Biology Letters, 2018 Background Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure.
Guodong Li +6 more
doaj +1 more source
Enhanced c-Fos expression in the central amygdala correlates with increased thigmotaxis in rats with peripheral nerve injury [PDF]
, 2015 Pain is associated with affective, cognitive and sensory dysfunction. Animal models can be used to observe ethologically relevant behaviours such as thigmotaxis, giving insight into how ongoing sensory abnormalities influence natural rodent behaviours ...
Rice, ASC
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2018 The cellular oncogene c-Fos (c-Fos) is a component of activator protein 1 (AP1), a master transcriptional regulator of cells. The suppression of c-Fos signaling by siRNA treatment resulted in significant induction of TLR4, which subsequently activates ...
Huynh T. Hop +10 more
doaj +1 more source
Novel spinal pathways identified by neuronal c-Fos expression after urethrogenital reflex activation in female guinea pigs [PDF]
, 2015 © 2014. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/Pudendal nerve-spinal pathways are involved in urethrogenital sensation, pain and sexual activity.
Gibbins, Ian Lewis +3 more
core +1 more source