Results 31 to 40 of about 19,750,598 (378)

c-Fos and Dusp1 confer non-oncogene addiction in BCR-ABL induced leukemia

Nature Network Boston, 2017
Tyrosine-kinase inhibitor (TKI) therapy for human cancers is not curative, and relapse occurs owing to the continued presence of tumor cells, referred to as minimal residual disease (MRD).
M. Kesarwani, Zachary Kincaid, A. Gomaa, E. Huber, Sara L. Rohrabaugh, Z. Siddiqui, Muhammad F Bouso, T. Latif, Ming-zheng Xu, K. Komurov, J. Mulloy, J. Cancelas, H. Grimes, M. Azam   +13 more
semanticscholar   +1 more source

Old players with a newly defined function: Fra-1 and c-Fos support growth of human malignant breast tumors by activating membrane biogenesis at the cytoplasm. [PDF]

PLoS ONE, 2013
A shared characteristic of tumor cells is their exacerbated growth. Consequently, tumor cells demand high rates of phospholipid synthesis required for membrane biogenesis to support their growth.
Ruben D Motrich, Gonzalo M Castro, Beatriz L Caputto   +2 more
doaj   +1 more source

p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models

Frontiers in Cellular Neuroscience, 2022
The activation of the p53 pathway has been associated with neuronal degeneration in different neurological disorders, including spinal muscular atrophy (SMA) where aberrant expression of p53 drives selective death of motor neurons destined to degenerate.
Jannik M. Buettner, Leonie Sowoidnich, Florian Gerstner, Beatriz Blanco-Redondo, Stefan Hallermann, Christian M. Simon   +5 more
doaj   +1 more source

Expression of the proto-oncogene c-fos and the immunolocalization of c-fos, phosphorylated c-fos and estrogen receptor beta in the human testis.

Histology and histopathology, 2009
Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation.
Araújo, Fabiano C., Oliveira, Cleida A., Reis, Augusto E., Del Puerto, Helen L., Martins, Almir S., Reis, Fernando M.   +5 more
openaire   +4 more sources

Antinociceptive Effects of Intrathecal Landiolol Injection in a Rat Formalin Pain Model [PDF]

, 2012
Perioperative beta-blocker administration has recently been recommended for patients undergoing cardiac or other surgery due to the beneficial cardiovascular effects of these agents.
Itano, Yoshitaro, Kaku, Ryuji, Kanzaki, Hirotaka, Matsuoka, Yoshikazu, Mizobuchi, Satoshi, Morita, Kiyoshi, Nishie, Hiroyuki, Obata, Norihiko, Ouchida, Mamoru, Taniguchi, Arata, Tomotsuka, Naoto   +10 more
core   +1 more source

The function of heterodimeric AP-1 comprised of c-Jun and c-Fos in activin mediated Spemann organizer gene expression. [PDF]

PLoS ONE, 2011
BACKGROUND:Activator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific role of AP-1 in activin signaling has not been elucidated during vertebrate development. METHODOLOGY/PRINCIPAL FINDINGS:We provide
Sung-Young Lee, Jaeho Yoon, Hyun-Shik Lee, Yoo-Seok Hwang, Sang-Wook Cha, Chul-Ho Jeong, Jong-Il Kim, Jae-Bong Park, Jae-Yong Lee, SungChan Kim, Mae Ja Park, Zigang Dong, Jaebong Kim   +12 more
doaj   +1 more source

The uppermost monoterpenes improving Cinnamomum camphora thermotolerance by serving signaling functions

Frontiers in Plant Science, 2022
Terpenes serve important functions in enhancing plant thermotolerance. Cinnamomum camphora mainly has eucalyptol (EuL), camphor (CmR), linalool (LnL) and borneol (BeL) chemotypes basing on the uppermost monoterpenes.
Chenyi Xu, Chenyi Xu, Bin Wang, Bin Wang, Qingyun Luo, Qingyun Luo, Yuandan Ma, Yuandan Ma, Tiefeng Zheng, Tiefeng Zheng, Yingying Wang, Yingying Wang, Yuyan Cai, Yuyan Cai, Zhaojiang Zuo, Zhaojiang Zuo   +15 more
doaj   +1 more source

Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos

Journal of Experimental Medicine, 2017
Pathological neovessels growing into the normally avascular photoreceptors cause vision loss in many eye diseases, such as age-related macular degeneration and macular telangiectasia.
Ye Sun, Zhiqiang Lin, Chi-Hsiu Liu, Y. Gong, Raffael G Liegl, Thomas W Fredrick, Steven S Meng, Samuel B Burnim, Zhongxiao Wang, James D. Akula, W. Pu, J. Chen, Lois E. H. Smith   +12 more
semanticscholar   +1 more source

C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance

Cellular & Molecular Biology Letters, 2018
Background Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure.
Guodong Li, Xiaoling Hu, Lu Sun, Xin Li, Jianfeng Li, Tongli Li, Xiaohui Zhang   +6 more
doaj   +1 more source

Expression of c-fos in hilar mossy cells of the dentate gyrus in vivo. [PDF]

, 2013
Granule cells (GCs) of the dentate gyrus (DG) are considered to be quiescent--they rarely fire action potentials. In contrast, the other glutamatergic cell type in the DG, hilar mossy cells (MCs) often have a high level of spontaneous activity based on ...
Amaral, Barouk, Bijak, Bijak, Blasco-Ibáñez, Brunner, Buckmaster, Buckmaster, Buckmaster, Chawla, Clelland, Deller, Deller, Derrick, Dragunow, Dragunow, Duffy, Fields, Freund, Frotscher, Fujise, Fujise, Ghadimi, Harley, Henze, Hernandez-Rabaza, Hofmann, Jinno, Jung, Kerr, Kesner, Larimer, Lee, Lee, Leranth, Leranth, Leutgeb, Lubke, McClung, McHugh, Mody, Morgan, Peng, Ribak, Scharfman, Scharfman, Scharfman, Scharfman, Scharfman, Scharfman, Scharfman, Sheng, Soltesz, Uchigashima, West, Williamson, Witter   +56 more
core   +2 more sources