c-Fos induction by gut hormones and extracellular ATP in osteoblastic-like cell lines [PDF]
, 2016 It is widely accepted that the c-Fos gene has a role in proliferation and differentiation of bone cells. ATP-induced c-Fos activation is relevant to bone homeostasis, because nucleotides that are present in the environment of bone cells can contribute to
A Gartland +36 more
core +1 more source
Neural Regeneration Research, 2015 c-Fos is a good biological marker for detecting the pathogenesis of central nervous system disorders. Few studies are reported on the change in myocardial infarction-induced c-Fos expression in the paralimbic regions. Thus, in this study, we investigated
Ji Yun Ahn +11 more
doaj +1 more source
Intracellular Mediators of c-fos Induction
Cold Spring Harbor Symposia on Quantitative Biology, 1988 Transcription of the c-fos proto-oncogene is rapidly and transiently induced in cells exposed to a remarkably wide range of external stimuli, including growth and differentiation factors, neurotransmitters, drugs, and mechanical stimuli (for review, see Curran 1988).
M Z, Gilman +6 more
openaire +2 more sources
c-Fos expression induced by electroacupuncture at the Zusanli point in rats submitted to repeated immobilization [PDF]
, 2003 In laboratory animals, acupuncture needs to be performed on either anesthetized or, if unanesthetized, restrained subjects. Both procedures up-regulate c-Fos expression in several areas of the central nervous system, representing therefore a major ...
Canteras, N.s. +3 more
core +3 more sources
c-Fos importance for brain development
Aging, 2015 c-Fos is an immediate early response gene involved in cell proliferation and differentiation after extracellular stimuli, whereas its deregulation has been associated to oncogenic progression. As other members of the FOS family proteins (Fra-1, Fra-2, FosB) and proteins of the ATF family, c-Fos can heterodimerize with members of the JUN family (c-Jun ...
Fabiola N, Velazquez +2 more
openaire +2 more sources
Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected [PDF]
, 2004 Polycystin-1, the polycystic kidney disease 1 gene product, has been implicated in several signaling complexes that are known to regulate essential cellular functions. We investigated the role of polycystin-1 in Wnt signaling and activator protein-1 (
Arnould +37 more
core +3 more sources
Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4. [PDF]
PLoS Pathogens, 2016 We investigated the mechanism of how the papillomavirus E2 transcription factor can activate promoters through activator protein (AP)1 binding sites. Using an unbiased approach with an inducible cell line expressing the viral transcription factor E2 and ...
Maria Delcuratolo +14 more
doaj +1 more source
The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP [PDF]
, 1988 Transcription of the c-fos proto-oncogene is rapidly induced by serum growth factors. A short c-fos DNA element, the serum response element (SRE), is required for this response to serum.
Gilman, M. Z.
core +1 more source
Lesions of retrosplenial cortex spare immediate-early gene activity in related limbic regions in the rat [PDF]
, 2018 The retrosplenial cortex forms part of a network of cortical and subcortical structures that have particular importance for spatial learning and navigation in rodents.
Aggleton, John +6 more
core +2 more sources
Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients. [PDF]
PLoS ONE, 2016 Although increased TNF-α has been considered to cause ineffective hematopoiesis in myelodysplastic syndromes (MDS), the mechanisms of TNF-α elevation are not known.
Yayoi Shikama +10 more
doaj +1 more source