Results 81 to 90 of about 19,750,598 (378)
Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos
Briso et al. find that c-fos expression in the mouse epidermis is sufficient to promote inflammation-mediated epidermal hyperplasia. c-Fos transcriptionally controls mmp10 and s100a7a15 expression in keratinocytes, promoting CD4 T-cell recruitment to the
Eva M. Briso+9 more
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Galanin/ Neuropeptide Y Y1 receptor interaction at the cellular and receptor level in the amygdala [PDF]
Galanin (GAL) interacts functionally with Neuropeptide Y Y1 receptor (Y1) in the nucleus tractus solitarius and the arcuate nucleus. Since GAL and Y1 participate in mood disorders, the aim of this work was to analyze GAL/Y1 interactions in the amygdala ...
Borroto-Escuela, Dasiel+8 more
core
Heterogeneous Nuclear Ribonucleoprotein R Cooperates with Mediator to Facilitate Transcription Reinitiation on the c-Fos Gene [PDF]
The c-fos gene responds to extracellular stimuli and undergoes robust but transient transcriptional activation. Here we show that heterogeneous nuclear ribonucleoprotein R (hnRNP R) facilitates transcription reinitiation of the c-fos promoter in vitro in
Fukuda Aya+7 more
core +1 more source
The dataset describes regional brain c-Fos expression and a component of maternal nest building behavior (“straw carrying”) in 5 late term pregnant rabbits that had been allowed to interact with straw (a nest building material) for a discrete period (30 ...
Hugo Cano-Ramírez+2 more
doaj
Twenty-four base pairs of the human antioxidant response element (hARE) are required for high basal transcription of the NAD(P)H:quinone oxidoreductase1 (NQO1) gene and its induction in response to xenobiotics and antioxidants.
R. Venugopal, A. Jaiswal
semanticscholar +1 more source
Engineering Highly Cellularized Living Materials via Mechanical Agitation
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani+9 more
wiley +1 more source
The small GTP-binding protein RhoA regulates c-Jun by a ROCK-JNK signaling axis [PDF]
RhoA regulates the actin cytoskeleton and the expres- sion of genes associated with cell proliferation. This includes c-fos and c-jun, which are members of the AP1 family of transcription factors that play a key role in normal and aberrant cell growth ...
Bernard, Ora+5 more
core +2 more sources
MPTP-induced increase in c-Fos- and c-Jun-like immunoreactivity in the monkey cerebellum
The transcription factors c-Fos and c-Jun have been described to be overexpressed following many pathological stimuli, but whether they are required for neurodegeneration or neuroprotection is still open.
D Necchi+4 more
doaj +1 more source
Advanced Oral Delivery Systems for Nutraceuticals
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang+4 more
wiley +1 more source