Results 181 to 190 of about 2,467,830 (354)

Controlling Metal‐Oxide Reducibility for Efficient C−H Bond Activation in Hydrocarbons [PDF]

, 2023
Guoqing Yang, Yiming Niu, Vita A. Kondratenko, Xianfeng Yi, Chang Liu, Bingsen Zhang, Evgenii V. Kondratenko, Zhong‐Wen Liu   +7 more
openalex   +1 more source

Synergistic C–H bond activation across molybdenum–iridium multiply bonded complexes: a cascade of transformations

International audienceeterobimetallic compounds offer unique opportunities for activating substrates through cooperative interactions between two distinct metal centers, potentially leading to catalytic reactivity beyond the reach of monometallic systems.
Camp, Clément, Maron, Laurent, Dubrawski, Zachary, del Rosal, Iker, Jeanneau, Erwann, Thieuleux, Chloé   +5 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

First selective direct mono-arylation of piperidines using ruthenium-catalyzed C–H activation [PDF]

, 2013
Maria Schwarz, Navid Dastbaravardeh, Karl Kirchner, Michael Schnürch, Marko D. Mihovilovič   +4 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Metal-Site Reducibility Governs C-H Activation and PAH Degradation in Ion-Exchanged Bentonite. [PDF]

Environ Sci Technol
Jin P, Denison SB, Zygourakis K, Alvarez PJJ, Senftle TP.   +4 more
europepmc   +1 more source

Deciphering the origin of million-fold reactivity observed for the open core diiron [HO–Fe^III–O–Fe^IVO]²⁺species towards C–H bond activation: role of spin-states, spin-coupling, and spin-cooperation

, 2020
Mursaleem Ansari, Dhurairajan Senthilnathan, Gopalan Rajaraman   +2 more
openalex   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Alkali metal cation effects for rapid C-H activation by iron(0) complexes. [PDF]

Chem Sci
Hidalgo N, Southwell KW, Donnelly RS, Mercado BQ, Krajewski SM, Wang X, Holland PL.   +6 more
europepmc   +1 more source

Promotional effects of chemisorbed oxygen and hydroxide in the activation of C–H and O–H bonds over transition metal surfaces

, 2016
David Hibbitts, Matthew Neurock
openalex   +2 more sources