Results 191 to 200 of about 29,149,024 (329)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Substitution, Elimination, and Integration of Methyl Groups in Terpenes Initiated by C-H Bond Functionalization. [PDF]

ACS Cent Sci
Kang YC, Wetterer RT, Karimov RR, Kojima M, Surke M, Martín-Torres I, Nicolai J, Elkin M, Hartwig JF.   +8 more
europepmc   +1 more source

Remote CH Bond Functionalizations

, 2023
Korvorapun, Korkit, Samanta, Ramesh C., Rogge, Torben, Ackermann, Lutz, Maiti, Debabrata, Guin, Srimanta   +5 more
openaire   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Connecting remote C-H bond functionalization and decarboxylative coupling using simple amines. [PDF]

Nat Chem, 2020
de Azambuja F, Yang MH, Feoktistova T, Selvaraju M, Brueckner AC, Grove MA, Koley S, Cheong PH, Altman RA.   +8 more
europepmc   +1 more source

Activation and functionalization of C-H bonds

Focus on Catalysts, 2005
openaire   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

In-situ noncovalent interaction of ammonium ion enabled C-H bond functionalization of polyethylene glycols. [PDF]

Nat Commun
Zhang Z, Lv X, Mu X, Zhao M, Wang S, Ke C, Ding S, Zhou D, Wang M, Zeng R.   +9 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Transition-Metal-Catalyzed Directed C-H Bond Functionalization with Iodonium Ylides: A Review of the Last 5 Years. [PDF]

Molecules
Liao J, Kong D, Gao X, Zhai R, Chen X, Wang S.   +5 more
europepmc   +1 more source