Results 171 to 180 of about 31,613,878 (290)

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho-extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3--kinase‑associated pathways. [PDF]

Mol Med Rep
Hu J, Cheng T, Zhang L, Sun B, Deng L, Xu H.   +5 more
europepmc   +1 more source

Chondrogenic medium in combination with a c-Jun N-terminal kinase inhibitor mediates engineered cartilage regeneration by regulating matrix metabolism and cell proliferation. [PDF]

Regen Biomater, 2023
Zhang P, Wang Q, Chen J, Ci Z, Zhang W, Liu Y, Wang X, Zhou G.   +7 more
europepmc   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

The FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas, Maria Pitou, Amalia Aggeli, Sotiris Varlamis, Theodora Choli‐Papadopoulou   +4 more
wiley   +1 more source

Inhibition of the Phospholipase Cε-c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties. [PDF]

Int J Mol Sci, 2022
Okada M, Nakagawa-Saito Y, Mitobe Y, Sugai A, Togashi K, Suzuki S, Kitanaka C.   +6 more
europepmc   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Suppression of Age-Related Macular Degeneration-like Pathology by c-Jun N-Terminal Kinase Inhibitor IQ-1S. [PDF]

Biomedicines, 2023
Zhdankina AA, Tikhonov DI, Logvinov SV, Plotnikov MB, Khlebnikov AI, Kolosova NG.   +5 more
europepmc   +1 more source

TaANT11‐4A enhances grain yield by orchestrating photosynthesis and carbohydrate metabolism through direct transcriptional activation

Journal of Integrative Plant Biology, EarlyView.
TaANT11‐4A is a positive regulator of wheat grain size and yield, directly activating TaEGY2, TaAAE1, and TaAAE2 to enhance photosynthesis and carbohydrate metabolism. The favorable Hap2 haplotype increases TaANT11‐4A expression and grain size, providing a genetic resource for breeding higher‐yielding wheat varieties.
Pengpeng Zhang, Jingjing Wen, Shan Gao, Jiajun Ma, Jiahui Jin, Xiaofei Ma, Wen‐Ting Liu, Juan Li, De‐Jun Han, Yue‐Qiang Zhang, Kun‐Ming Chen   +10 more
wiley   +1 more source

Pharmacological Inhibition of c-Jun N-Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice. [PDF]

Liver Int
Stettler F, Knedla L, Hagen M, von Bülow V, Müller H, Tschuschner A, Zahner D, Haeberlein S, Moescheid MF, Windhorst A, Burg-Roderfeld M, Glebe D, Moreira BP, Lesieur C, Schmid A, Falcone FH, Grevelding CG, Roeb E, Roderfeld M.   +18 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

C-X-C motif chemokine ligand 13 and the C-X-C motif chemokine receptor 5-c-Jun N-terminal kinase-nuclear factor kappa B-matrix metalloproteinase 9 axis in oral squamous cell carcinoma metastasis. [PDF]

J Dent Sci
Liu JF, Lin KC, Hsu PC, Chang TM, Chen P, Sun YS.   +5 more
europepmc   +1 more source