Results 151 to 159 of about 82,350 (159)

c-Maf Induces Monocytic Differentiation and Apoptosis in Bipotent Myeloid Progenitors

Blood, 1999
The transcriptional mechanisms that drive colony-forming unit granulocyte-macrophage (CFU-GM) myeloid progenitors to differentiate into cells of either the granulocytic or monocytic lineage are not fully understood. We have shown that the c-Maf and c-Myb transcription factors physically interact in myeloid cells to form inhibitory complexes that hinder
S P, Hegde, J, Zhao, R A, Ashmun, L H, Shapiro   +3 more
openaire   +2 more sources

Regulation of GM-CSF expression by the transcription factor c-Maf

Journal of Allergy and Clinical Immunology, 2007
Inflammation is a key feature of asthma and allergic disease. The proinflammatory cytokines IL-4, IL-5, and IL-13 are clustered on chromosome 5q with GM-CSF in close proximity, and each of these cytokines has been implicated in the pathogenesis of inflammatory disease.
Gilmour, Jane, Cousins, David J, Richards, David F, Sattar, Zahid, Lee, Tak H, Lavender, Paul   +5 more
openaire   +3 more sources

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

Science, 2012
Telling Sandpaper from Satin Pacinian corpuscles are mechano-receptors tuned to detect high-frequency, low-amplitude, signals. Found in human palm and fingertips, they are useful for discrimination of rough and smooth textures, a sensitivity seemingly amplified by the ridges of fingerprints.
Hagen, Wende, Stefan G, Lechner, Cyril, Cheret, Steeve, Bourane, Maria E, Kolanczyk, Alexandre, Pattyn, Katja, Reuter, Francis L, Munier, Patrick, Carroll, Gary R, Lewin, Carmen, Birchmeier   +10 more
openaire   +2 more sources

MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional Macrophages

Science, 2009
Self-Renewing Macrophages The capacity for self-renewal is associated with progenitor cell populations and is lost upon differentiation. Aziz et al. (p. 867 ) discovered an exception to this rule when mouse monocytes and macrophages ...
Aziz, Athar, Soucie, Erinn, Sarrazin, Sandrine, Sieweke, Michael   +3 more
openaire   +3 more sources

Functional Analysis of Transcription Factor c-Maf in Embryonic Hematopoiesis.

Blood, 2009
Abstract Abstract 3646 Poster Board III-582 c-Maf is one of the large Maf (musculoaponeurotic fibrosarcoma) transcription factors that belong to the AP1 super family of basic leucine zipper proteins. c-Maf has been shown to be important for the regulation of IL-4 and IL-21 gene expression in T-helper-2 cells
Manabu Kusakabe, Michito Hamada, Megumi Nakamura, Takashi Kudo, Haruhiko Ninomiya, Satoru Takahashi   +5 more
openaire   +1 more source

c-Maf determines IL-10 regulation during Th17 polarization (47.22)

The Journal of Immunology, 2009
Abstract IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. Gene array analysis on Stat6 and T-bet double deficient Th17 cells identified the Th2 transcription factor c-Maf to be synergistically up-regulated by IL-6 plus TGFβ, and associated with Th17 IL-10 production.
Jiangnan Xu, Yu Yang, Girdhari Lal, Jordi C. Ochando, Jonathan S. Bromberg, Yaozhong Ding   +5 more
openaire   +1 more source

Transkriptionsfaktor c-maf reguliert Dünndarmentzündung

Zeitschrift für Gastroenterologie, 2015
B Weigmann, A Nemetz, C Becker, LH Glimcher, MF Neurath   +4 more
openaire   +1 more source

Regulation of c-maf by IL-2

Cytokine, 2009
Rani, Aradhana, Kelly, Audrey, Berhan, Lemlem Tewolde, Jurevic, Stipo, Ragheb, Jack, Lavender, Paul, John, Susan   +6 more
openaire   +2 more sources

C-MAF INHIBITS EOMES EXPRESSION AND CD8 EFFECTOR RESPONSES.

Transplantation, 2006
openaire   +1 more source