Results 221 to 230 of about 20,395,316 (257)

Welcoming c-MAF to the macrophage transcription factor VAM-ily

Science Immunology, 2021
The transcription factor c-MAF regulates perivascular macrophage phenotypes across tissues, including white adipose tissue, where its loss from murine vasculature–associated macrophages leads to increased vascularization and protection from metabolic syndrome (see the related Research Article by Moura Silva
Pieter A. Louwe, Charlotte L. Scott
openaire   +2 more sources

c-Maf Expression in Angioimmunoblastic T-cell Lymphoma

American Journal of Surgical Pathology, 2007
The oncogene c-Maf was recently found to be overexpressed in approximately 50% of multiple myeloma cases, and a role for c-Maf in promoting cyclin D2 expression has been postulated. We previously examined c-Maf expression in various T-cell lymphomas by reverse-transcription polymerase chain reaction and found extremely elevated c-Maf levels in ...
Yoshiko Idate, Murakami, Yasushi, Yatabe, Teruhiro, Sakaguchi, Eiichi, Sasaki, Yoriko, Yamashita, Naoki, Morito, Keigyou, Yoh, Yuuki, Fujioka, Fumihiko, Matsuno, Hiroyuki, Hata, Hiroaki, Mitsuya, Shigehiko, Imagawa, Atsushi, Suzuki, Hiroyasu, Esumi, Masaharu, Sakai, Satoru, Takahashi, Naoyoshi, Mori   +16 more
openaire   +2 more sources

Proliferation in the posterior region of the lens of c-maf-/- mice

Current Eye Research, 2001
To examine the involvement of the c-maf gene in the proliferation of the lens cells.Eyes of the E13 and E18 stages of the wild-type and c-maf-/- mice were analyzed by BrdU incorporation assay, TUNEL assay and immunocytochemistry using a anti-P27(KIP1) and a anti-P57(KIP2) antibody.In the E13 and E18 c-maf mutant lens, BrdU-positive cells were detected ...
K, Yoshida, J I, Kim, J, Imaki, I, Hiromi, S, Nishi, H, Matsuda, T, Harada, C, Harada, S, Ohno, M, Sakai   +9 more
openaire   +2 more sources

Molecular insights into dimerization inhibition of c-Maf transcription factor

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2014
The Maf protein family belongs to the activator protein 1 (AP-1) superfamily of transcription factors that bind specific DNA target sequences through a basic region and exploit a leucine zipper (LZ) motif for protein-protein interactions leading to homo- or hetero-dimerization.
Pellegrino, Sara, RONDA, Luca, Annoni, Chiara, Contini, Alessandro, Erba, Emanuela, Gelmi, Maria Luisa, PIANO, Riccardo, PAREDI, Gianluca, MOZZARELLI, Andrea, BETTATI, Stefano   +9 more
openaire   +5 more sources

Regulation of GM-CSF expression by the transcription factor c-Maf

Journal of Allergy and Clinical Immunology, 2007
Inflammation is a key feature of asthma and allergic disease. The proinflammatory cytokines IL-4, IL-5, and IL-13 are clustered on chromosome 5q with GM-CSF in close proximity, and each of these cytokines has been implicated in the pathogenesis of inflammatory disease.
Gilmour, Jane, Cousins, David J, Richards, David F, Sattar, Zahid, Lee, Tak H, Lavender, Paul   +5 more
openaire   +3 more sources

Upregulation of miR-155 regulates group 2 innate lymphoid cells by targeting c-maf in allergic rhinitis.

European Journal of Pharmacology, 2020
Group 2 innate lymphoid cells (ILC2s) and Th2 type immune response are critically involved in the pathogenesis of allergic rhinitis (AR), and this pathological process is influenced by microRNAs-mediated post-transcriptional regulation. The present study
Ya-Qiong Zhu, Yue-Hui Liu, Xinhua Zhu, Zhi Wang, Mei-Qun Wang   +4 more
semanticscholar   +1 more source

USF2/FIP Associates with the b-Zip Transcription Factor, c-Maf, via Its bHLH Domain and Inhibits c-Maf DNA Binding Activity

Biochemical and Biophysical Research Communications, 1997
In screening for proteins that interact with the basic zipper (bZip) transcription factor, c-Maf, we isolated USF2/FIP. USF2 is a member of the bHLH-Zip protein family, possessing a basic (b) DNA binding region, a helix-loop-helix (HLH) motif, and a leucine zipper (Zip) structure.
C, Kurschner, J I, Morgan
openaire   +2 more sources

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

Science, 2012
Telling Sandpaper from Satin Pacinian corpuscles are mechano-receptors tuned to detect high-frequency, low-amplitude, signals. Found in human palm and fingertips, they are useful for discrimination of rough and smooth textures, a sensitivity seemingly amplified by the ridges of fingerprints.
Hagen, Wende, Stefan G, Lechner, Cyril, Cheret, Steeve, Bourane, Maria E, Kolanczyk, Alexandre, Pattyn, Katja, Reuter, Francis L, Munier, Patrick, Carroll, Gary R, Lewin, Carmen, Birchmeier   +10 more
openaire   +2 more sources

Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro

Biochemical and Biophysical Research Communications, 2016
The large Maf transcription factors c-Maf and MafB are expressed in macrophage-lineage hematopoietic cells, but the expression patterns of MafB and c-Maf in macrophage subtypes and tissue-resident macrophages have not been fully analyzed. First, we analyzed MafB and c-Maf protein expression in tissue-resident macrophages.
Dhouha Daassi, Michito Hamada, Hyojung Jeon, Yuki Imamura, Mai Thi Nhu Tran, Satoru Takahashi   +5 more
openaire   +2 more sources

C-MAF Oncogene Dysregulation in Multiple Myeloma: Frequency and Biological Relevance

Leukemia & Lymphoma, 2003
To investigate the frequency and possible biological consequences of c-maf dysregulation, we designed c-maf and IL-4 real-time RT-PCR assays for determination of c-maf and IL-4 mRNA levels. Using the c-maf real-time RT-PCR assay, we tested a panel of 14 B-cell lines, 135 diagnostic bone marrow (BM) samples from patients with multiple myeloma and 10 BM ...
Thomas, Rasmussen, Lene Meldgaard, Knudsen, Inger Marie S, Dahl, Hans Erik, Johnsen   +3 more
openaire   +2 more sources