Results 231 to 240 of about 81,067 (257)

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Impact of Model Parameterisation and Variance Component Estimates on Genomic Predictions of Carcass Traits in Montana Composite Cattle

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT This study evaluated the influence of variance component (VC) estimates, obtained from different models and two relationship matrices, pedigree‐based (BLUP) and genomic information‐based (ssGBLUP), on genomic predictions of carcass traits in Montana composite cattle.
Caroline Assis Almeida   +9 more
wiley   +1 more source

Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez   +6 more
wiley   +1 more source
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Transcription factor c-Maf-targeted cancer immunotherapy

Trends in Cancer, 2023
In innate immune cells, the transcription factor cellular musculoaponeurotic fibrosarcoma (c-Maf) influences cell fate and function through molecular and metabolic programming, thereby influencing immune homeostasis and antitumor immunity. We discuss recent c-Maf landmark discoveries with a focus on the immunosuppressive tumor microenvironment (TME ...
Yunke Wang, Fuming Qiu, Jun Yan
openaire   +2 more sources

c-Maf: The magic wand that turns on LSEC fate

Cell Stem Cell, 2022
In this issue of Cell Stem Cell, Gómez-Salinero et al. (2022) identify c-Maf as a driver for murine liver sinusoidal endothelial cell (LSEC) fate and function during liver development, homeostasis, and repair. Similarly, c-Maf defines human LSECs, and its overexpression specializes generic HUVECs into functional induced-LSECs, potentiating regenerative
Anna R, Smith, Valerie, Gouon-Evans
openaire   +2 more sources

Correlation between the expression level of c-maf and glutathione peroxidase-3 in c-maf −/− mice kidney and c-maf overexpressed renal tubular cells

Biochemical and Biophysical Research Communications, 2006
Large mafs are transcriptional factors and members of the basic leucine zipper (b-Zip) superfamily. Since we previously identified expression of c-maf in mouse kidney, we presently investigated the mRNA expression profile in the kidney of c-maf gene knockout mice by using DNA microarray, and plasma glutathione peroxidase-3 (GPx3) was predominantly ...
S, Shirota   +7 more
openaire   +2 more sources

Welcoming c-MAF to the macrophage transcription factor VAM-ily

Science Immunology, 2021
The transcription factor c-MAF regulates perivascular macrophage phenotypes across tissues, including white adipose tissue, where its loss from murine vasculature–associated macrophages leads to increased vascularization and protection from metabolic syndrome (see the related Research Article by Moura Silva
Pieter A. Louwe, Charlotte L. Scott
openaire   +2 more sources

c-Maf Expression in Angioimmunoblastic T-cell Lymphoma

American Journal of Surgical Pathology, 2007
The oncogene c-Maf was recently found to be overexpressed in approximately 50% of multiple myeloma cases, and a role for c-Maf in promoting cyclin D2 expression has been postulated. We previously examined c-Maf expression in various T-cell lymphomas by reverse-transcription polymerase chain reaction and found extremely elevated c-Maf levels in ...
Yoshiko Idate, Murakami   +16 more
openaire   +2 more sources

Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of c-maf knockout mice kidney and liver

Biochemical and Biophysical Research Communications, 2004
Maf is a family of oncogenes which encodes a nuclear bZip transcription factor protein and has been originally identified from the avian oncogenic retrovirus, AS42. Maf genes have been reported to have critical roles in embryological development and cellular differentiation.
Junko, Imaki   +7 more
openaire   +2 more sources

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