Results 61 to 70 of about 82,350 (159)
Early loss of splenic Tfh cells in SIV-infected rhesus macaques [PDF]
Follicular T helper cells (Tfh), a subset of CD4 T lymphocytes, provide crucial help to B cells in the production of antigen-specific antibodies. Although several studies have analyzed the dynamics of Tfh cells in peripheral blood and lymph nodes (LNs ...
Andreani, Guadalupe +10 more
core +5 more sources
The rapid emergence of drug resistant pathogens is a major threat which has warranted the development of alternative strategies to combat infectious diseases. In this work, we have tested the anti-virulent activity of Meldrum’s acid activated furan (MAF)
Ajmal Sadik +14 more
doaj +1 more source
We have isolated a selectively deglycosylated form of vitamin D binding protein (DBP-maf) generated from systemically available DBP by a human pancreatic cancer cell line.
Oliver Kisker +10 more
doaj +1 more source
Multiple Myeloma : an update on disease biology and therapy [PDF]
Multiple myeloma is a malignancy of immunoglobulin producing plasma cells. Clinical features include bone pain due to lytic bone lesions or pathological fractures, anemia, symptomatic hypercalcemia, renal insufficiency, recurrent infections and ...
Cook, Rachel J., Dingli, David
core
Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production [PDF]
IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells.
Cherukur, Yesesri +8 more
core +1 more source
Lightweight 3rd generation Al–Cu–Li alloy AA2050 was severely deformed via Multi Axial Forging (MAF) at 170 °C followed by artificial aging at 150 °C.
C Jagadeesh +4 more
doaj +1 more source
Role of dendritic cells in the induction of regulatory T cells [PDF]
Dendritic cells (DCs) play a key role in initiating immune responses and maintaining immune tolerance. In addition to playing a role in thymic selection, DCs play an active role in tolerance under steady state conditions through several mechanisms which ...
Rahul Kushwah, Jim Hu
core +3 more sources
c-MAF protein expression in multiple myeloma
Background. The c-MAF oncogene, located in the 16q23.2 region, encodes the protein of the same name, a transcription factor whose role continues to be studied. Given the activating effect of the c-MAF transcription factor in enhancing the interaction between the tumor cell and the bone marrow stroma, we hypothesized that c-MAF protein expression would ...
M. V. Solov’eva +5 more
openaire +1 more source
Methionine adenosyltransferases in liver cancer. [PDF]
Methionine adenosyltransferases (MATs) are essential enzymes for life as they produce S-adenosylmethionine (SAMe), the biological methyl donor required for a plethora of reactions within the cell.
Barbier-Torres, Lucia +4 more
core

