Results 71 to 80 of about 82,350 (159)
Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]
, 2012 Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.Rose, Markus A., Schubert, Ralf, Schulze, Johannes, Voss, Sandra, Zielen, Stefan, Zissler, Ulrich +5 morecore +2 more sourcesTSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand. [PDF]
, 2017 T follicular helper cells (Tfh) are important regulators of humoral responses. Human Tfh polarization pathways have been thus far associated with Th1 and Th17 polarization pathways. How human Tfh cells differentiate in Th2-skewed environments is unknown. Alain Hovnanian, Alculumbre, Andrea Cavani, Andrea Chiricozzi, Ballesteros-Tato, Bernasconi, Bernhard Homey, Brandt, Briot, Bryant, Choi, Coline Trichot, Coquet, Crotty, Deenick, Elisabetta Volpe, Furio, Giacomin, Glatman Zaretsky, Gould, Grewe, Gringhuis, Hatzi, He, Hovnanian, Ito, Ito, Jacquemin, Kemeny, Kim, Kroenke, Kusam, Leyva-Castillo, Liang, Liu, Locci, Lonati, Lucia Pattarini, Ma, Ma, Marco Romanelli, Maximilien Grandclaudon, Melanie Durand, Morita, Nakazawa, Nies, Niu, O’Shea, Pène, Ramalingam, Schmitt, Schmitt, Schmitt, Shin, Sofia Bogiatzi, Soumelis, Stefania Madonna, Stephan Meller, Tangye, Toshiyuki Hori, Trinchieri, Ueno, Van Roey, Vassili Soumelis, Volpe, Volpe, Wang, Weinstein, Ying, Yusuf, Zela Keuylian, Ziegler +71 morecore +3 more sourcesc-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4+ T cells [PDF]
Journal of Leukocyte Biology, 2009 Abstract c-Maf directly induces IL-21 expression by activating IL-21 promoter and CNS-2 enhancer through MARE site and TGF-β suppresses c-Maf-induced IL-21 expression. Previous studies have shown that IL-6 potently induces IL-21 production in CD4+ T cells, whereas TGF-β inhibits IL-6-induced IL-21 production in CD4+ T ...Yukiko, Hiramatsu, Akira, Suto, Daisuke, Kashiwakuma, Hiroko, Kanari, Shin-ichiro, Kagami, Kei, Ikeda, Koichi, Hirose, Norihiko, Watanabe, Michael J, Grusby, Itsuo, Iwamoto, Hiroshi, Nakajima +10 moreopenaire +2 more sourcesCombinatorial transcriptional regulation establishes subtype-appropriate synaptic properties in auditory neurons
Cell ReportsSummary: Neurons develop diverse synapses that vary in content, morphology, and size. Although transcriptional regulators of neurotransmitter identity are known, it remains unclear how synaptic features are patterned among neuronal subtypes.Isle Bastille, Lucy Lee, Cynthia Moncada-Reid, Wei-Ming Yu, Austen Sitko, Andrea Yung, Mina Zamani, Nele Christophersen, Reza Maroofian, Hamid Galehdari, Norbert Babai, Barbara Vona, Tobias Moser, Lisa Goodrich +13 moredoaj +1 more sourceIL-21 induces IL-22 production in CD4+ T-cells [PDF]
, 2014 IL-22 produced by innate lymphoid cells (ILCs) and CD4+ T cells plays an important role in host defense and mucosal homeostasis, thus it is important to investigate the mechanisms that regulate IL-22 production.Burns, Evan J., Kumar, Deepak, Mascanfroni, Ivan D., Nadeau, Meghan, Patel, Bonny, Quintana, Francisco J., Santiago, Andrezza, Tukpah, Ann-Marcia, Wu, Chuan, Yeste, Ada +9 morecore +1 more sourceMechanisms of immunological tolerance in central nervous system inflammatory demyelination. [PDF]
, 2015 Multiple sclerosis is a complex autoimmune disease of the central nervous system that results in a disruption of the balance between pro-inflammatory and anti-inflammatory signals in the immune system.Anderton, Ando, Andres, Apetoh, Astier, Awasthi, Bacchetta, Bacchetta, Barrat, Batten, Bennett, Borsellino, Brunkow, Cedeno-Laurent, Chen, Chen, Dalla Libera, Darrasse-Jeze, David, Dominguez-Villar, Durelli, El-Behi, Faria, Fitzgerald, Fitzgerald, Fitzgerald, Fletcher, Fontenot, Frisullo, Gagliani, Gandhi, Garin, Getts, Getts, Gregory, Groux, Haak, Haas, Haas, Harrington, Hilliard, Hong, Hori, Huan, Huang, Huber, Hunter, Iellem, Ilarregui, Jiang, Joller, Kipnis, Kohm, Komiyama, Kopcow, Korn, Korn, Korporal, Kroenke, Kuniyasu, Langrish, Laouar, Leech, Leonard, Li, Liblau, Lutterotti, Magnani, Mariathasan, Markiewicz, Martinez-Forero, Mascanfroni, McGeachy, Mehling, Miller, Mosmann, Muls, Noseworthy, O'Connor, Ohnmacht, Peng, Pflanz, Pflanz, Pitkanen, Pot, Pot, Pot, Rabinovich, Ramgolam, Ratts, Read, Rostami, Rovetto, Russell, Sakaguchi, Secor, Segal, Sela, Smith, Stephens, Stumhofer, Sundstedt, Takahashi, Takeda, Tigno-Aranjuez, Toscano, Turley, Tzartos, Uyttenhove, Veen, Venken, Venken, Vieira, Viglietta, Villarino, Voskuhl, Wang, Wang, Weiner, Wildbaum, Wildin, Xu, Yamaguchi, Yamazaki, Yang, Yang, Zhang, Zhang, Zhang, Zhang +129 morecore +2 more sourcesThe regulation of IL-10 expression [PDF]
, 2014 Interleukin (IL)-10 is an important immunoregulatory cytokine and an understanding of how IL-10 expression is controlled is critical in the design of immune intervention strategies.A Banerjee, A Blokzijl, A Boonstra, A Chakrabarti, A Chaudhry, A Gaba, A Kimura, A Kitani, A Neininger, A Sharma, A Villagra, AD Edwards, AD Edwards, AD Foey, AG Jarnicki, AK Yi, AM Smith, AN Ahyi, B Corre, B Csoka, B Lenhard, B Li, B Schaljo, C Dong, C Jiang, C Kemper, C Platzer, C Pot, C Pot, C Tudor, CD Dumitru, CF Fuqua, CG Lee, CG Lee, CY Brown, D Jarrossay, D Nandan, D Yu, DC Fitzgerald, DM Reid, E Carballo, E Carballo, E Cretney, E Hitti, E Kanters, EA Jones, EC Slack, EM Benkhart, EY Chang, EY Chung, F Dodeller, F Kaiser, F Kratochvill, F Ma, F Macian, F Radtke, FJ Sheedy, FW McNab, G Brewer, G Chen, G Friec Le, G Guarda, G Kassiotis, G Stoecklin, G Stoecklin, G Strassmann, G Vahedi, G Vahedi, GA Martins, GD Kalliolias, GI Forte, H Chi, H Hacker, H Sandler, H Wang, H Yu, HC Chang, HD Brightbill, HD Chang, HJ Lee, IC Ho, II Ivanov, J Das, J Rengarajan, J Shoemaker, J Sun, J Xu, J Zhu, J Zhu, JA Zhang, JI Kim, JM Kim, JS Gerber, JS Stumhofer, K Clark, KA Mowen, KD Mayer-Barber, KF MacKenzie, KJ Staples, KM Dennehy, KM Murphy, KW Moore, L Apetoh, L Kim, L Wei, L Ziegler-Heitbrock, LA O’Neill, M Batten, M Brook, M Bros, M Ciofani, M Hammer, M Karin, M Lucas, M Martin, M Martin, M Ohtani, M Saraiva, M Saraiva, M Saraiva, M Tone, M Veldhoen, MJ Aman, MJ Pattison, MJ Powell, MK Levings, N Kadowaki, N Kedersha, N Mori, NC Rogers, O Ananieva, P Anderson, P Ivanov, P Li, PC Hollenhorst, PE Fields, PJ Murray, Q Yu, R Grenningloh, R Lang, R Spolski, R Tussiwand, RI Nurieva, RJ Brownlie, RJ Johnston, S Agrawal, S Brenner, S Cao, S Cao, S Dillon, S Dillon, S Gerondakis, S Kusam, S Rutz, SH Im, SJ Szabo, SS Iyer, T Gantke, T Ito, T Jenuwein, T Kawai, T Krausgruber, T Owaki, T Weichhart, TL Murphy, TM Franks, V Romano-Spica, VR Ramirez-Carrozzi, W Ma, W Zheng, WT Watford, X Hu, X Liu, X Pichon, X Zhang, Y Alvarez, Y Motomura, YW Liu, ZH Nemeth, ZY Wang +179 morecore +1 more source
