Results 261 to 270 of about 18,976,803 (305)

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability. [PDF]

J Transl Med
He C, Tang C, Guo J, Yin X, Zhu Q, Fang C.   +5 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

PPIL2 suppression induces cellular senescence and inhibits proliferation in hepatocellular carcinoma via c-myc/p21 axis. [PDF]

J Biol Chem
Chen X, Zhang Z, Yan Z, Du X, Wang J, Liu X, Hu L, Kuang Z, He K, Zhang J, Han Y.   +10 more
europepmc   +1 more source

Gene Expression and Immunohistochemical Analyses of c-Myc in Canine and Feline Soft Tissue Fibrosarcomas. [PDF]

Animals (Basel)
Al-Jameel W, Al-Saidya A, Salah B, Ismail H, Al-Mahmood S.   +4 more
europepmc   +1 more source

Wogonin Suppresses Non-Small Cell Lung Cancer Growth in Association with Oxidative Stress, c-Myc/GPX4 Downregulation and Ferroptosis-Related Responses. [PDF]

Antioxidants (Basel)
Xiang H, Liu H, Jiang R, Tang X, Zhao L, Zeng D, Zhang Y, Xie J, Shi L, Yang L.   +9 more
europepmc   +1 more source

RAD18 facilitates cancer progression and immunosuppression via the AKT/mTOR/c-Myc axis: a multi-omics analysis. [PDF]

NPJ Precis Oncol
Zhu J, Huang Q, Liang Q, Yi W.
europepmc   +1 more source

SLPI/FBW7/c-Myc Axis Reduces Gemcitabine Sensitivity in PDAC by Enhancing Glycolysis and Impairing NK Cell Immunity. [PDF]

Cancer Sci
Chen H, Li X, Zhu W, Mu Y, Zhang G, Zhang Y, Cheng Y, Zhou W.   +7 more
europepmc   +1 more source

Letter to the Editor Regarding "EXT2 promotes sarcoma progression and immune evasion via the AKT/c-Myc/PD-L1 axis: a multi-omics and validation study". [PDF]

J Transl Med
Song Q, Liu Y, Dou F.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

c-Myc-driven Hepatocarcinogenesis

Anticancer Research, 2021
Dysregulation of the c-Myc gene is frequently found in human hepatocellular carcinoma (HCC), often accompanied by genetic and epigenetic alterations in other cancer-related genes. Here, we investigated the tumorigenic potential of c-Myc in diverse genetic environments in which the Ras, Wnt/β-catenin, Sonic hedgehog, or P53 pathways were either ...
Hyuk, Moon, Hyunjung, Park, Simon Weonsang, Ro   +2 more
openaire   +2 more sources