Results 121 to 130 of about 278,471 (164)

Sirt1 deacetylates c-Myc and promotes c-Myc/Max association

The International Journal of Biochemistry & Cell Biology, 2011
The c-Myc oncoprotein plays critical roles in multiple biological processes by controlling cell proliferation, apoptosis, differentiation, and metabolism. Especially, c-Myc is frequently overexpressed in many human cancers and widely involved in tumorigenesis.
Beibei, Mao, Guowei, Zhao, Xiang, Lv, Hou-Zao, Chen, Zheng, Xue, Ben, Yang, De-Pei, Liu, Chih-Chuan, Liang   +7 more
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Function of the c‐Myc oncoprotein

The FASEB Journal, 1992
The c‐Myc protein, the product of the c‐myc proto‐oncogene, is a nuclear phosphoprotein with DNA binding properties. Deregulated c‐myc expression participates in the development of experimentally induced tumors, and its expression appears to be abnormal
G J, Kato, C V, Dang
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The many faces of c-MYC

Archives of Biochemistry and Biophysics, 2003
The proto-oncogene c-MYC is implicated in various physiological processes-cell growth, proliferation, loss of differentiation, and cell death (apoptosis). Oncogenic c-MYC implies constitutive or deregulated expression of c-MYC and is associated with many human cancers often with poor prognosis.
Stella, Pelengaris, Mike, Khan
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A transcriptional repressor of c-myc

Nature, 1989
In murine plasmacytomas there is deregulated transcription of a translocated c-myc allele and undetectable transcription of the normal, unrearranged c-myc allele. Deregulated c-myc transcription probably contributes to the transformed phenotype of the tumour cells, whereas repression of the normal allele probably reflects the normal turn-off of c-myc ...
E, Kakkis, K J, Riggs, W, Gillespie, K, Calame   +3 more
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Activation of the c-myc Oncogene

1986
Activated forms of the c-myc oncogene have been linked to cell transformation in a variety of mammalian and avian tumors. Several mechanisms of gene activation have been described, but each mechanism gives rise to constitutive levels of expression, usually no higher than that found in proliferating normal cells.
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Expression of c-myc and Pvt1

1990
Deregulated expression of c-myc secondary to chromosomal alterations is a constant feature of mouse plasmacytomas, rat immunocytomas and human Burkitt lymphomas (Mushinski, 1988). One feature of deregulated expression of c-myc is that all plasmacytomas have high levels of c-myc transcripts, no matter whether their chromosome 15 was interrupted by a ...
J F, Mushinski, R M, Skurla, J, Goodnight, D, Siwarski, K, Huppi   +4 more
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???????????????????? ???????????????? c-myc ?? ?????????????? ???????????????? ?????????????????? ????????????

2019
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c-Myc and apoptosis

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1995
G, Packham, J L, Cleveland
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c-myc

Melanoma Research, 1997
J Chana, R Grover, G D Wilson, R Sanders
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The MYC oncogene — the grand orchestrator of cancer growth and immune evasion

Nature Reviews Clinical Oncology, 2021
Renumathy Dhanasekaran, Wadie D Mahauad-Fernandez, Anja Deutzmann   +2 more
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