Results 211 to 220 of about 282,710 (262)

Triglyceride lipase PNPLA2-independent suppression of c-MYC signaling by the metabolic coactivator ABHD5 in prostate cancer. [PDF]

J Biol Chem
Lotvola A, Chen G, Zhou G, Granneman JG, Wang J.   +4 more
europepmc   +1 more source

KAT3B acts as an oncogene in PCa by mediating the succinylation of c-Myc and promoting its stability. [PDF]

World J Surg Oncol
Nie W, Cha S, Fu Q.
europepmc   +1 more source

c-Myc transactivates CFL1 to induce senescence-like phenotype and potentiate the bystander effects for the migration and proliferation in lung cancer cells. [PDF]

Cell Death Discov
Chou YT, Leu JD, Yang WY, Li CH, Lin MY, Kao CW, Chang YC, Hsiao M, Lee YJ.   +8 more
europepmc   +1 more source

Epithelial AhR Suppresses Allergen-Induced Oxidative Stress and Senescence via c-Myc Regulation. [PDF]

Antioxidants (Basel)
Chen Z, Gu W, Wan R, Zeng Y, Xiang X, Ouyang R, Gao P.   +6 more
europepmc   +1 more source

Letter regarding HOXA9 drives lymphatic metastasis by activating the c-MYC-glycolysis-lactate axis in gastric cancer. [PDF]

J Transl Med
Zhang X, Wang Z, Xie J, Zhang F.
europepmc   +1 more source

Correction: TTC36 promotes proliferation and drug resistance in hepatocellular carcinoma cells by inhibiting c-Myc degradation. [PDF]

Cell Death Dis
Shao F, Wang R, Li X, Hu Y, Zhang Z, Cai J, Yang J, Feng X, Ren S, Huang Z, Xie Y.   +10 more
europepmc   +1 more source

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c-Myc-driven Hepatocarcinogenesis

Anticancer Research, 2021
Dysregulation of the c-Myc gene is frequently found in human hepatocellular carcinoma (HCC), often accompanied by genetic and epigenetic alterations in other cancer-related genes. Here, we investigated the tumorigenic potential of c-Myc in diverse genetic environments in which the Ras, Wnt/β-catenin, Sonic hedgehog, or P53 pathways were either ...
Hyuk, Moon, Hyunjung, Park, Simon Weonsang, Ro   +2 more
openaire   +2 more sources

Association with C-Myc: An Alternated Mechanism for c-Myc Function

1995
The c-myc proto-oncogene encodes a ubiquitously expressed nuclear phospho-protein that is involved in the control of cellular proliferation and differentiation (1, 2, 3). Alteration of the c-myc locus by chromosomal translocation, amplification or retroviral insertion is often associated with tumorigenesis in different species including humans (1, 3 ...
A, Shrivastava, K, Calame
openaire   +2 more sources

Sirt1 deacetylates c-Myc and promotes c-Myc/Max association

The International Journal of Biochemistry & Cell Biology, 2011
The c-Myc oncoprotein plays critical roles in multiple biological processes by controlling cell proliferation, apoptosis, differentiation, and metabolism. Especially, c-Myc is frequently overexpressed in many human cancers and widely involved in tumorigenesis.
Beibei, Mao, Guowei, Zhao, Xiang, Lv, Hou-Zao, Chen, Zheng, Xue, Ben, Yang, De-Pei, Liu, Chih-Chuan, Liang   +7 more
openaire   +2 more sources

A transcriptional repressor of c-myc

Nature, 1989
In murine plasmacytomas there is deregulated transcription of a translocated c-myc allele and undetectable transcription of the normal, unrearranged c-myc allele. Deregulated c-myc transcription probably contributes to the transformed phenotype of the tumour cells, whereas repression of the normal allele probably reflects the normal turn-off of c-myc ...
E, Kakkis, K J, Riggs, W, Gillespie, K, Calame   +3 more
openaire   +2 more sources