Results 251 to 260 of about 19,205,329 (382)

Correction: TTC36 promotes proliferation and drug resistance in hepatocellular carcinoma cells by inhibiting c-Myc degradation. [PDF]

Cell Death Dis
Shao F, Wang R, Li X, Hu Y, Zhang Z, Cai J, Yang J, Feng X, Ren S, Huang Z, Xie Y.   +10 more
europepmc   +1 more source

c-Myc inhibits myoblast differentiation and promotes myoblast proliferation and muscle fibre hypertrophy by regulating the expression of its target genes, miRNAs and lincRNAs

Cell Death and Differentiation, 2018
W. Luo, Jiahui Chen, Limin Li, Xueyi Ren, Tian Cheng, Shiyi Lu, R. Lawal, Q. Nie, Xiquan Zhang, O. Hanotte   +9 more
semanticscholar   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

NIBAN2 Stimulates Glioma Growth by Regulating the JAK2/STAT3/c-Myc Pathway. [PDF]

Cancer Med
Chen ZM, Mou L, Pan YH, Feng C, Liu J, Zhang JJ, Yan CX.   +6 more
europepmc   +1 more source

Data from Potent Synergistic Effect on C-Myc–Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

, 2023
Yanqi Xie, Wen Zhang, Lichao Guo, Liliia M. Kril, Kristin L. Begley, Vitaliy M. Sviripa, Xi Chen, Xifu Liu, Eun Y. Lee, Daheng He, Chi Wang, Tianyan Gao, Xiaoqi Liu, B. Mark Evers, David S. Watt, Chunming Liu   +15 more
openalex   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

PI3K/AKT/mTOR pathway and c-Myc inhibit hepatocyte suspension under simulated microgravity. [PDF]

NPJ Microgravity
Xiong Y, Ma C, Xie J, Chen Z, Zhang K, Lei X.   +5 more
europepmc   +1 more source

c-Myc cooperates with activated Ras to induce the cdc2 promoter.

, 1994
T L Born, Jeffrey A. Frost, Axel H. Schönthal, George C. Prendergast, James R. Feramisco   +4 more
openalex   +2 more sources

Supplementary Figure 2 from Triggering Fbw7-Mediated Proteasomal Degradation of c-Myc by Oridonin Induces Cell Growth Inhibition and Apoptosis

, 2023
Huilin Huang, Hengyou Weng, Lu‐Qin Wang, Chun-Hong Yu, Qiao-Juan Huang, Panpan Zhao, Jun-Zhi Wen, Hui Zhou, Liang‐Hu Qu   +8 more
openalex   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source