Results 261 to 270 of about 19,205,329 (382)

The m6A reader YTHDF1 facilitates nasopharyngeal carcinoma proliferation and migration via c-MYC. [PDF]

J Biol Chem
Han P, Xiao Z, Xia T, Wu T, Li S, Ye Y, Zeng H, Zeng M, Zhong Q, Huang X.   +9 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

ASS1 facilitates T-ALL progression via the arginine-mediated mTORC1/c-Myc signaling pathway. [PDF]

Sci Rep
Zhang Z, Liu X, Wu Q, Liang J, Zhao Y, Deng J, Wang Y, Yu Q, Ye Z, Zhu H, Lin J.   +10 more
europepmc   +1 more source

Fucoxanthin suppresses the malignant progression of ovarian cancer by inactivating STAT3/c-Myc signaling. [PDF]

, 2023
Zhan Zhang, Youqun Wang, Jianhua Li
openalex  

Oncogenic C-Myc Induces Replication Stress by Increasing Cohesins Chromatin Occupancy at Ctcf Sites

, 2022
Silvia Peripolli, Tanya Singh, Harshil Patel, Letícia Meneguello, Koshiro Kiso, Peter H. Thorpe, Cosetta Bertoli, Robertus Antonius Maria de Bruin   +7 more
openalex   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

HDAC5 deficiency induces intrinsic resistance to KRAS inhibition by disrupting c-Myc acetylation-ubiquitination homeostasis. [PDF]

J Clin Invest
Chen T, Yu H, Wang K, Qin G, Zhao Y, Liang X, Li Y, Zou T, Liu J, Zhao J, Liu Z, Wei R, Wang B, Gou S, Yin T, Wu H, Jin X, Zhou Y.   +17 more
europepmc   +1 more source

c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism

Molecular and Cellular Biology, 1999
C. Dang
semanticscholar   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

HOXA9 drives lymphatic metastasis by activating the c-MYC-glycolysis-lactate axis in gastric cancer. [PDF]

J Transl Med
Lu T, Shen G, Huang T, Mao X, He J, Hu Y.   +5 more
europepmc   +1 more source